| 1 | Thu Aug 29 | at UL Monroe | L14-30 | 0-1 | .000 | Malone Stadium ยท Monroe, LA |
| 2 | Sat Sep 7 | vs TBD | W58-7 | 1-1 | .500 | Mississippi Veterans Memorial Stadium |
| 3 | Sat Sep 14 | vs Southern | W33-15 | 2-1 | .667 | Mississippi Veterans Memorial Stadium |
| 4 | Sat Sep 21 | at Grambling | L20-41 | 2-2 | .500 | Eddie G. Robinson Memorial Stadium |
| 5 | Sat Sep 28 | at Texas So | W43-14 | 3-2 | .600 | Shell Energy Stadium |
| 6 | Sat Oct 5 | vs Alabama A&M | W45-38 | 4-2 | .667 | Ladd-Peebles Stadium |
| 8 | Sat Oct 19 | vs FAMU | W35-21 | 5-2 | .714 | Mississippi Veterans Memorial Stadium |
| 9 | Sat Oct 26 | at Bethune | W37-17 | 6-2 | .750 | Daytona Stadium |
| 10 | Sat Nov 2 | vs AR-Pine Bluff | W41-3 | 7-2 | .778 | Mississippi Veterans Memorial Stadium |
| 11 | Sat Nov 9 | vs Miss Valley St | W51-14 | 8-2 | .800 | Mississippi Veterans Memorial Stadium |
| 12 | Sat Nov 16 | at Alabama St | W16-10 | 9-2 | .818 | ASU Football Stadium |
| 13 | Sat Nov 23 | at Alcorn St | W48-10 | 10-2 | .833 | Spinks-Casem Stadium |
| 15 | Sat Dec 7 | vsSouthern | W41-13 | 11-2 | .846 | Mississippi Veterans Memorial Stadium |
| BOWLS | Sat Dec 14 | at SC State | W28-7 | 12-2 | .857 | Mercedes-Benz Stadium |
