| 1 | Sun Sep 5 | at FAMU | W7-6 | 1-0 | 1.000 | Hard Rock Stadium |
| 2 | Sat Sep 11 | vsTennessee St | W38-16 | 2-0 | 1.000 | Simmons Bank Liberty Stadium |
| 3 | Sat Sep 18 | atUL Monroe | L7-12 | 2-1 | .667 | Malone Stadium ยท Monroe, LA |
| 4 | Sat Sep 25 | vsTBD | W24-17 | 3-1 | .750 | Mississippi Veterans Memorial Stadium |
| 5 | Sat Oct 9 | atAlabama A&M | W61-15 | 4-1 | .800 | Louis Crews Stadium |
| 6 | Sat Oct 16 | vsAlabama St | W28-7 | 5-1 | .833 | Mississippi Veterans Memorial Stadium |
| 7 | Sat Oct 23 | vsBethune | W42-12 | 6-1 | .857 | Mississippi Veterans Memorial Stadium |
| 8 | Sat Oct 30 | atMiss Valley St | W28-19 | 7-1 | .875 | Rice-Totten Stadium |
| 9 | Sat Nov 6 | vsTexas So | W41-21 | 8-1 | .889 | Mississippi Veterans Memorial Stadium |
| 10 | Sat Nov 13 | atSouthern | W21-17 | 9-1 | .900 | A.W. Mumford Stadium |
| 11 | Sat Nov 20 | vsAlcorn St | W24-10 | 10-1 | .909 | Mississippi Veterans Memorial Stadium |
| 12 | Sat Dec 4 | vsPrairie View | W27-10 | 11-1 | .917 | Mississippi Veterans Memorial Stadium |
| BOWLS | Sat Dec 18 | vsSC State | L10-31 | 11-2 | .846 | Mercedes-Benz Stadium |
