Wed September 22, 2021

• FINAL
  

  Blue Jays1
  

  Rays7
• FINAL
  

  Nationals7
  

  Marlins5
• FINAL
  

  Orioles3
  

  Phillies4
• FINAL
  

  Rangers3
  

  Yankees7
• FINAL
  

  Mets5
  

  Red Sox12
• FINAL
  

  Twins5
  

  Cubs4
• FINAL
  

  Cardinals10
  

  Brewers2
• FINAL
  

  Dodgers5
  

  Rockies10
• FINAL/12
  

  Astros9
  

  Angels5
• FINAL
  

  Mariners4
  

  Athletics1
• FINAL
  

  Braves9
  

  D-backs2
• FINAL
  

  Giants8
  

  Padres6
• POSTPONED
  

  Pirates
  

  Reds
• POSTPONED
  

  White Sox
  

  Tigers
• POSTPONED
  

  Royals
  

  Guardians