| 1 | Sat Aug 30 | vs Holy Cross | W19-17 | 1-0 | 1.000 | Huskie Stadium · Dekalb, IL |
| 2 | Fri Sep 5 | atMaryland | L9-20 | 1-1 | .500 | SECU Stadium · College Park, MD |
| 3 | Sat Sep 20 | atMississippi St | L10-38 | 1-2 | .333 | Davis Wade Stadium · Starkville, MS |
| 4 | Sat Sep 27 | vsSDSU | L3-6 | 1-3 | .250 | Huskie Stadium · Dekalb, IL |
| 5 | Sat Oct 4 | vsMiami OH | L14-25 | 1-4 | .200 | Huskie Stadium · Dekalb, IL |
| 6 | Sat Oct 11 | atE Michigan | L10-16 | 1-5 | .167 | Rynearson Stadium · Ypsilanti, MI |
| 7 | Sat Oct 18 | atOhio | L21-48 | 1-6 | .143 | Peden Stadium · Athens, OH |
| 8 | Sat Oct 25 | vsBall State | W21-7 | 2-6 | .250 | Huskie Stadium · Dekalb, IL |
| 9 | Wed Nov 5 | atToledo | L3-42 | 2-7 | .222 | Glass Bowl · Toledo, OH |
| 10 | Wed Nov 12 | atUMass | W45-3 | 3-7 | .300 | Warren McGuirk Alumni Stadium · Amherst, MA |
| 11 | Tue Nov 18 | vsW Michigan | L19-35 | 3-8 | .273 | Huskie Stadium · Dekalb, IL |
| 12 | Fri Nov 28 | vsKent State | L31-35 | 3-9 | .250 | Huskie Stadium · Dekalb, IL |
