| 1 | Sat Sep 3 | at Nevada | L14-38 | 0-1 | .000 | Mackay Stadium · Reno, NV |
| 2 | Sat Sep 10 | vsFIU | W41-12 | 1-1 | .500 | Bobcat Stadium (TX) · San Marcos, TX |
| 3 | Sat Sep 17 | at#17Baylor | L7-42 | 1-2 | .333 | Floyd Casey Stadium · Waco, TX |
| 4 | Sat Sep 24 | vsHou Christian | W34-0 | 2-2 | .500 | Bobcat Stadium (TX) · San Marcos, TX |
| 5 | Sat Oct 1 | atJMU | L13-40 | 2-3 | .400 | Bridgeforth Stadium/Zane Showker Field · Harrisonburg, VA |
| 6 | Sat Oct 8 | vsAppalachian St | W36-24 | 3-3 | .500 | Bobcat Stadium (TX) · San Marcos, TX |
| 7 | Sat Oct 15 | atTroy | L14-17 | 3-4 | .429 | Veterans Memorial Stadium · Troy, AL |
| 8 | Sat Oct 22 | vsSouthern Miss | L14-20 | 3-5 | .375 | Bobcat Stadium (TX) · San Marcos, TX |
| 9 | Sat Nov 5 | atUL Monroe | L30-31 | 3-6 | .333 | Malone Stadium · Monroe, LA |
| 10 | Sat Nov 12 | atSouth Alabama | L21-38 | 3-7 | .300 | Hancock Whitney Stadium · Mobile, AL |
| 11 | Sat Nov 19 | vsArkansas St | W16-13 | 4-7 | .364 | Bobcat Stadium (TX) · San Marcos, TX |
| 12 | Sat Nov 26 | vsLouisiana | L13-41 | 4-8 | .333 | Bobcat Stadium (TX) · San Marcos, TX |
