Tue November 16, 2021

• FINAL
  

  Howard

  81
  

  5Villanova-29½

  100
• FINAL
  

  Wright St

  52
  

  6Purdue-16½

  96
• FINAL
  

  Gardner-Webb

  52
  

  7Duke-21

  92
• FINAL
  

  South Alabama

  68
  

  14Alabama-20½

  73
• FINAL
  

  Saint Louis

  74
  

  11Memphis-10½

  90
• FINAL
  

  Virginia

  47
  

  15Houston-5½

  67
• FINAL
  

  18UNC-12½

  94
  

  Charleston

  83