Wed December 29, 2021

• FINAL
  

  High Point

  68
  

  10Michigan St-22½

  81
• FINAL
  

  Nicholls

  90
  

  3Purdue-29

  104
• FINAL
  

  16LSU

  55
  

  11Auburn-4½

  70
• FINAL
  

  15Seton Hall

  65
  

  21Providence-2½

  70
• FINAL
  

  Missouri

  56
  

  18Kentucky-20½

  83
• FINAL
  

  Nevada

  61
  

  6Kansas-17½

  88
• FINAL
  

  Illinois St

  85
  

  24Wisconsin-17

  89
• FINAL
  

  14Tennessee

  68
  

  19Alabama-7

  73
• POSTPONED
  

  2Duke
  

  Clemson
• CANCELLED
  

  Temple
  

  22Villanova-17