| 1 | Sat Sep 12 | vs Hou Christian | W35-33 | 1-0 | 1.000 | Jones AT&T Stadium · Lubbock, TX |
| 2 | Sat Sep 26 | vs#8Texas | L56-63 (OT) | 1-1 | .500 | Jones AT&T Stadium · Lubbock, TX |
| 3 | Sat Oct 3 | atKansas St | L21-31 | 1-2 | .333 | Bill Snyder Family Stadium · Manhattan, KS |
| 4 | Sat Oct 10 | at#24Iowa State | L15-31 | 1-3 | .250 | Jack Trice Stadium · Ames, IA |
| 5 | Sat Oct 24 | vsWest Virginia | W34-27 | 2-3 | .400 | Jones AT&T Stadium · Lubbock, TX |
| 6 | Sat Oct 31 | vs#24Oklahoma | L28-62 | 2-4 | .333 | Jones AT&T Stadium · Lubbock, TX |
| 7 | Sat Nov 7 | atTCU | L18-34 | 2-5 | .286 | Amon G. Carter Stadium · Fort Worth, TX |
| 8 | Sat Nov 14 | vsBaylor | W24-23 | 3-5 | .375 | Jones AT&T Stadium · Lubbock, TX |
| 9 | Sat Nov 28 | at#23Oklahoma St | L44-50 | 3-6 | .333 | Boone Pickens Stadium · Stillwater, OK |
| 10 | Sat Dec 5 | vsKansas | W16-13 | 4-6 | .400 | Jones AT&T Stadium · Lubbock, TX |
