| 1 | Sat Sep 3 | vs Grambling | W58-3 | 1-0 | 1.000 | Centennial Bank Stadium · Jonesboro, AR |
| 2 | Sat Sep 10 | at#3Ohio State | L12-45 | 1-1 | .500 | Ohio Stadium · Columbus, OH |
| 3 | Sat Sep 17 | atMemphis | L32-44 | 1-2 | .333 | Simmons Bank Liberty Stadium · Memphis, TN |
| 4 | Sat Sep 24 | atOld Dominion | L26-29 | 1-3 | .250 | S.B. Ballard Stadium · Norfolk, VA |
| 5 | Sat Oct 1 | vsUL Monroe | W45-28 | 2-3 | .400 | Centennial Bank Stadium · Jonesboro, AR |
| 6 | Sat Oct 8 | vsJMU | L20-42 | 2-4 | .333 | Centennial Bank Stadium · Jonesboro, AR |
| 7 | Sat Oct 15 | atSouthern Miss | L19-20 | 2-5 | .286 | M. M. Roberts Stadium · Hattiesburg, MS |
| 8 | Sat Oct 22 | atLouisiana | L18-38 | 2-6 | .250 | Cajun Field · Lafayette, LA |
| 9 | Sat Oct 29 | vsSouth Alabama | L3-31 | 2-7 | .222 | Centennial Bank Stadium · Jonesboro, AR |
| 10 | Sat Nov 12 | vsUMass | W35-33 | 3-7 | .300 | Centennial Bank Stadium · Jonesboro, AR |
| 11 | Sat Nov 19 | atTexas St | L13-16 | 3-8 | .273 | Bobcat Stadium (TX) · San Marcos, TX |
| 12 | Sat Nov 26 | vsTroy | L19-48 | 3-9 | .250 | Centennial Bank Stadium · Jonesboro, AR |
