| 1 | Sat Sep 5 | vs Ball State | 12:30 PM | 0-0 | .000 | Ohio Stadium · Columbus, OH |
| 2 | Sat Sep 12 | at5Texas | 7:30 PM | 0-0 | .000 | DKR-Texas Memorial Stadium · Austin, TX |
| 3 | Sat Sep 19 | vsKent State | 12:00 PM | 0-0 | .000 | Ohio Stadium · Columbus, OH |
| 4 | Sat Sep 26 | vsIllinois | TBD | 0-0 | .000 | Ohio Stadium · Columbus, OH |
| 5 | Sat Oct 3 | at22Iowa | TBD | 0-0 | .000 | Kinnick Stadium · Iowa City, IA |
| 6 | Sat Oct 10 | vsMaryland | TBD | 0-0 | .000 | Ohio Stadium · Columbus, OH |
| 7 | Sat Oct 17 | at6Indiana | TBD | 0-0 | .000 | Memorial Stadium · Bloomington, IN |
| 8 | Sat Oct 31 | at14USC | TBD | 1-0 | 1.000 | Los Angeles Memorial Coliseum · Los Angeles, CA |
| 9 | Sat Nov 7 | vs2Oregon | TBD | 0-0 | .000 | Ohio Stadium · Columbus, OH |
| 10 | Sat Nov 14 | vsNorthwestern | TBD | 0-0 | .000 | Ohio Stadium · Columbus, OH |
| 11 | Sat Nov 21 | atNebraska | TBD | 0-0 | .000 | Memorial Stadium · Lincoln, NE |
| 12 | Sat Nov 28 | vs16Michigan | 12:00 PM | 0-0 | .000 | Ohio Stadium · Columbus, OH |
