| 1 | Sat Aug 30 | at USC | L13-73 | 0-1 | .000 | Los Angeles Memorial Coliseum · Los Angeles, CA |
| 2 | Sat Sep 6 | atMarshall | W21-20 | 1-1 | .500 | Joan C. Edwards Stadium · Huntington, WV |
| 3 | Sat Sep 13 | vsSMU | L10-28 | 1-2 | .333 | Robert W. Plaster Stadium · Springfield, MO |
| 4 | Sat Sep 20 | vsUT Martin | W42-10 | 2-2 | .500 | Robert W. Plaster Stadium · Springfield, MO |
| 5 | Sat Sep 27 | vsWestern KY | L22-27 | 2-3 | .400 | Robert W. Plaster Stadium · Springfield, MO |
| 6 | Wed Oct 8 | atMTSU | W22-20 | 3-3 | .500 | Johnny "Red" Floyd Stadium · Murfreesboro, TN |
| 7 | Wed Oct 22 | atNew Mexico St | W24-17 (OT) | 4-3 | .571 | Aggie Memorial Stadium · Las Cruces, NM |
| 8 | Wed Oct 29 | vsFIU | W28-21 | 5-3 | .625 | Robert W. Plaster Stadium · Springfield, MO |
| 9 | Sat Nov 8 | atLiberty | W21-17 | 6-3 | .667 | Williams Stadium (VA) · Lynchburg, VA |
| 10 | Sat Nov 15 | vsUTEP | W38-24 | 7-3 | .700 | Robert W. Plaster Stadium · Springfield, MO |
| 11 | Sat Nov 22 | atKennesaw St | L34-41 | 7-4 | .636 | Fifth Third Stadium |
| 12 | Sat Nov 29 | vsLouisiana Tech | L30-42 | 7-5 | .583 | Robert W. Plaster Stadium · Springfield, MO |
