| 1 | Fri Aug 30 | at Oregon St | W52-36 | 1-0 | 1.000 | Reser Stadium · Corvallis, OR |
| 2 | Sat Sep 7 | vsMcNeese | W56-14 | 2-0 | 1.000 | Boone Pickens Stadium · Stillwater, OK |
| 3 | Sat Sep 14 | atTulsa | W40-21 | 3-0 | 1.000 | Chapman Stadium · Tulsa, OK |
| 4 | Sat Sep 21 | at#12Texas | L30-36 | 3-1 | .750 | DKR-Texas Memorial Stadium · Austin, TX |
| 5 | Sat Sep 28 | vs#24Kansas St | W26-13 | 4-1 | .800 | Boone Pickens Stadium · Stillwater, OK |
| 6 | Sat Oct 5 | atTexas Tech | L35-45 | 4-2 | .667 | Jones AT&T Stadium · Lubbock, TX |
| 7 | Sat Oct 19 | vs#18Baylor | L27-45 | 4-3 | .571 | Boone Pickens Stadium · Stillwater, OK |
| 8 | Sat Oct 26 | at#23Iowa State | W34-27 | 5-3 | .625 | Jack Trice Stadium · Ames, IA |
| 9 | Sat Nov 2 | vsTCU | W34-27 | 6-3 | .667 | Boone Pickens Stadium · Stillwater, OK |
| 10 | Sat Nov 16 | vsKansas | W31-13 | 7-3 | .700 | Boone Pickens Stadium · Stillwater, OK |
| 11 | Sat Nov 23 | atWest Virginia | W20-13 | 8-3 | .727 | Milan Puskar Stadium · Morgantown, WV |
| 12 | Sat Nov 30 | vs#7Oklahoma | L16-34 | 8-4 | .667 | Boone Pickens Stadium · Stillwater, OK |
| BOWLS | Fri Dec 27 | atTexas A&M | L21-24 | 8-5 | .615 | Kyle Field · College Station, TX |
