| 1 | Thu Sep 3 | vs South Alabama | L21-32 | 0-1 | .000 | M. M. Roberts Stadium · Hattiesburg, MS |
| 2 | Sat Sep 19 | vsLouisiana Tech | L30-31 | 0-2 | .000 | M. M. Roberts Stadium · Hattiesburg, MS |
| 3 | Sat Sep 26 | vsTulane | L24-66 | 0-3 | .000 | M. M. Roberts Stadium · Hattiesburg, MS |
| 4 | Sat Oct 3 | atNorth Texas | W41-31 | 1-3 | .250 | DATCU Stadium · Denton, TX |
| 5 | Sat Oct 10 | vsFAU | PPD | 3-7 | .300 | M. M. Roberts Stadium · Hattiesburg, MS |
| 6 | Sat Oct 17 | atUTEP | PPD | 3-7 | .300 | Sun Bowl · El Paso, TX |
| 7 | Sat Oct 24 | atLiberty | L35-56 | 1-4 | .200 | Williams Stadium (VA) · Lynchburg, VA |
| 8 | Sat Oct 31 | vsRice | L6-30 | 1-5 | .167 | M. M. Roberts Stadium · Hattiesburg, MS |
| 9 | Sat Nov 7 | vsNorth Alabama | W24-13 | 2-5 | .286 | M. M. Roberts Stadium · Hattiesburg, MS |
| 10 | Sat Nov 14 | atWestern KY | L7-10 | 2-6 | .250 | Houchens Industries-L.T. Smith Stadium · Bowling Green, KY |
| 11 | Sat Nov 21 | vsUTSA | L20-23 | 2-7 | .222 | M. M. Roberts Stadium · Hattiesburg, MS |
| 14 | Thu Dec 10 | vsFAU | W45-31 | 3-7 | .300 | M. M. Roberts Stadium · Hattiesburg, MS |
