Sat January 29, 2022

• FINAL
  

  9Duke-6½

  74
  

  Louisville

  65
• FINAL
  

  La Salle

  69
  

  25Davidson-15

  77
• FINAL
  

  Michigan

  67
  

  10Michigan St-4

  83
• FINAL
  

  21Xavier-1½

  74
  

  Creighton

  64
• FINAL
  

  Arizona St

  56
  

  3Arizona-21½

  67
• FINAL
  

  St John's

  62
  

  14Villanova-13½

  73
• FINAL
  

  24Illinois-5½

  59
  

  Northwestern

  56
• FINAL
  

  20UConn-9½

  57
  

  DePaul

  50
• FINAL
  

  California

  72
  

  15USC-12½

  79
• FINAL
  

  7Houston-6½

  63
  

  UCF

  49
• FINAL
  

  Portland

  72
  

  2Gonzaga-32½

  104
• FINAL
  

  Stanford

  43
  

  7UCLA-11½

  66