| 1 | Sat Sep 4 | vs N'Western St | W44-14 | 1-0 | 1.000 | DATCU Stadium · Denton, TX |
| 2 | Sat Sep 11 | atSMU | L12-35 | 1-1 | .500 | Gerald J. Ford Stadium · Dallas, TX |
| 3 | Sat Sep 18 | vsUAB | L6-40 | 1-2 | .333 | DATCU Stadium · Denton, TX |
| 4 | Sat Sep 25 | atLouisiana Tech | L17-24 | 1-3 | .250 | Joe Aillet Stadium · Ruston, LA |
| 5 | Sat Oct 9 | atMissouri | L35-48 | 1-4 | .200 | Memorial Stadium/Faurot Field · Columbia, MO |
| 6 | Fri Oct 15 | vsMarshall | L21-49 | 1-5 | .167 | DATCU Stadium · Denton, TX |
| 7 | Sat Oct 23 | vsLiberty | L26-35 | 1-6 | .143 | DATCU Stadium · Denton, TX |
| 8 | Sat Oct 30 | atRice | W30-24 (OT) | 2-6 | .250 | Rice Stadium · Houston, TX |
| 9 | Sat Nov 6 | atSouthern Miss | W38-14 | 3-6 | .333 | M. M. Roberts Stadium · Hattiesburg, MS |
| 10 | Sat Nov 13 | vsUTEP | W20-17 | 4-6 | .400 | DATCU Stadium · Denton, TX |
| 11 | Sat Nov 20 | atFIU | W49-7 | 5-6 | .455 | Riccardo Silva Stadium · Miami, FL |
| 12 | Sat Nov 27 | vs#22UTSA | W45-23 | 6-6 | .500 | DATCU Stadium · Denton, TX |
| BOWLS | Thu Dec 23 | atMiami OH | L14-27 | 6-7 | .462 | Yager Stadium · Oxford, OH |
