| 1 | Thu Aug 28 | vs C Arkansas | W61-6 | 1-0 | 1.000 | Memorial Stadium/Faurot Field · Columbia, MO |
| 2 | Sat Sep 6 | vsKansas | W42-31 | 2-0 | 1.000 | Memorial Stadium/Faurot Field · Columbia, MO |
| 3 | Sat Sep 13 | vsLouisiana | W52-10 | 3-0 | 1.000 | Memorial Stadium/Faurot Field · Columbia, MO |
| 4 | Sat Sep 20 | vsSouth Carolina | W29-20 | 4-0 | 1.000 | Memorial Stadium/Faurot Field · Columbia, MO |
| 5 | Sat Sep 27 | vsUMass | W42-6 | 5-0 | 1.000 | Memorial Stadium/Faurot Field · Columbia, MO |
| 6 | Sat Oct 11 | vs#8Alabama | L24-27 | 5-1 | .833 | Memorial Stadium/Faurot Field · Columbia, MO |
| 7 | Sat Oct 18 | atAuburn | W23-17 (2OT) | 6-1 | .857 | Jordan-Hare Stadium · Auburn, AL |
| 8 | Sat Oct 25 | at#10Vanderbilt | L10-17 | 6-2 | .750 | FirstBank Stadium · Nashville, TN |
| 9 | Sat Nov 8 | vs#3Texas A&M | L17-38 | 6-3 | .667 | Memorial Stadium/Faurot Field · Columbia, MO |
| 10 | Sat Nov 15 | vsMississippi St | W49-27 | 7-3 | .700 | Memorial Stadium/Faurot Field · Columbia, MO |
| 11 | Sat Nov 22 | at#8Oklahoma | L6-17 | 7-4 | .636 | Memorial Stadium · Norman, OK |
| 12 | Sat Nov 29 | atArkansas | W31-17 | 8-4 | .667 | Razorback Stadium · Fayetteville, AR |
