| 1 | Thu Aug 29 | vs Murray St | W51-0 | 1-0 | 1.000 | Memorial Stadium/Faurot Field · Columbia, MO |
| 2 | Sat Sep 7 | vs Buffalo | W38-0 | 2-0 | 1.000 | Memorial Stadium/Faurot Field · Columbia, MO |
| 3 | Sat Sep 14 | vs #24Boston College | W27-21 | 3-0 | 1.000 | Memorial Stadium/Faurot Field · Columbia, MO |
| 4 | Sat Sep 21 | vs Vanderbilt | W30-27 (2OT) | 4-0 | 1.000 | Memorial Stadium/Faurot Field · Columbia, MO |
| 6 | Sat Oct 5 | at #25Texas A&M | L10-41 | 4-1 | .800 | Kyle Field · College Station, TX |
| 7 | Sat Oct 12 | at UMass | W45-3 | 5-1 | .833 | Warren McGuirk Alumni Stadium · Amherst, MA |
| 8 | Sat Oct 19 | vs Auburn | W21-17 | 6-1 | .857 | Memorial Stadium/Faurot Field · Columbia, MO |
| 9 | Sat Oct 26 | at #15Alabama | L0-34 | 6-2 | .750 | Bryant-Denny Stadium · Tuscaloosa, AL |
| 11 | Sat Nov 9 | vs Oklahoma | W30-23 | 7-2 | .778 | Memorial Stadium/Faurot Field · Columbia, MO |
| 12 | Sat Nov 16 | at #21South Carolina | L30-34 | 7-3 | .700 | Williams-Brice Stadium · Columbia, SC |
| 13 | Sat Nov 23 | at Mississippi St | W39-20 | 8-3 | .727 | Davis Wade Stadium · Starkville, MS |
| 14 | Sat Nov 30 | vs Arkansas | W28-21 | 9-3 | .750 | Memorial Stadium/Faurot Field · Columbia, MO |
| BOWLS | Mon Dec 30 | vs Iowa | W27-24 | 10-3 | .769 | Memorial Stadium/Faurot Field · Columbia, MO |
