| 1 | Sat Aug 31 | vs Furman | W76-0 | 1-0 | 1.000 | Vaught-Hemingway Stadium · Oxford, MS |
| 2 | Sat Sep 7 | vs MTSU | W52-3 | 2-0 | 1.000 | Vaught-Hemingway Stadium · Oxford, MS |
| 3 | Sat Sep 14 | at Wake Forest | W40-6 | 3-0 | 1.000 | Allegacy Federal Credit Union Stadium · Winston-Salem, NC |
| 4 | Sat Sep 21 | vs Georgia So | W52-13 | 4-0 | 1.000 | Vaught-Hemingway Stadium · Oxford, MS |
| 5 | Sat Sep 28 | vs Kentucky | L17-20 | 4-1 | .800 | Vaught-Hemingway Stadium · Oxford, MS |
| 6 | Sat Oct 5 | at South Carolina | W27-3 | 5-1 | .833 | Williams-Brice Stadium · Columbia, SC |
| 7 | Sat Oct 12 | at #13LSU | L26-29 (OT) | 5-2 | .714 | Tiger Stadium · Baton Rouge, LA |
| 9 | Sat Oct 26 | vs Oklahoma | W26-14 | 6-2 | .750 | Vaught-Hemingway Stadium · Oxford, MS |
| 10 | Sat Nov 2 | at Arkansas | W63-31 | 7-2 | .778 | Razorback Stadium · Fayetteville, AR |
| 11 | Sat Nov 9 | vs #3Georgia | W28-10 | 8-2 | .800 | Vaught-Hemingway Stadium · Oxford, MS |
| 13 | Sat Nov 23 | at Florida | L17-24 | 8-3 | .727 | Ben Hill Griffin Stadium · Gainesville, FL |
| 14 | Fri Nov 29 | vs Mississippi St | W26-14 | 9-3 | .750 | Vaught-Hemingway Stadium · Oxford, MS |
| BOWLS | Thu Jan 2 | vs Duke | W52-20 | 10-3 | .769 | Vaught-Hemingway Stadium · Oxford, MS |
