| 1 | Sat Sep 2 | vs Mercer | W73-7 | 1-0 · #22 | 1.000 | Vaught-Hemingway Stadium · Oxford, MS |
| 2 | Sat Sep 9 | at24Tulane | W37-20 | 2-0 · #20 | 1.000 | Yulman Stadium · New Orleans, LA |
| 3 | Sat Sep 16 | vsGeorgia Tech | W48-23 | 3-0 · #17 | 1.000 | Vaught-Hemingway Stadium · Oxford, MS |
| 4 | Sat Sep 23 | at13Alabama | L10-24 | 3-1 · #15 | .750 | Bryant-Denny Stadium · Tuscaloosa, AL |
| 5 | Sat Sep 30 | vs13LSU | W55-49 | 4-1 · #20 | .800 | Vaught-Hemingway Stadium · Oxford, MS |
| 6 | Sat Oct 7 | vsArkansas | W27-20 | 5-1 · #16 | .833 | Vaught-Hemingway Stadium · Oxford, MS |
| 7 | Sat Oct 21 | atAuburn | W28-21 | 6-1 · #13 | .857 | Jordan-Hare Stadium · Auburn, AL |
| 8 | Sat Oct 28 | vsVanderbilt | W33-7 | 7-1 · #12 | .875 | Vaught-Hemingway Stadium · Oxford, MS |
| 9 | Sat Nov 4 | vsTexas A&M | W38-35 | 8-1 · #10 | .889 | Vaught-Hemingway Stadium · Oxford, MS |
| 10 | Sat Nov 11 | at2Georgia | L17-52 | 8-2 · #9 | .800 | Sanford Stadium · Athens, GA |
| 11 | Sat Nov 18 | vsUL Monroe | W35-3 | 9-2 · #13 | .818 | Vaught-Hemingway Stadium · Oxford, MS |
| 12 | Thu Nov 23 | atMississippi St | W17-7 | 10-2 · #12 | .833 | Davis Wade Stadium · Starkville, MS |
| BOWLS | Sat Dec 30 | at10Penn State | W38-25 | 11-2 · #11 | .846 | Beaver Stadium · University Park, PA |
