| 1 | Sat Aug 31 | vs E Kentucky | W56-7 | 1-0 | 1.000 | Davis Wade Stadium · Starkville, MS |
| 2 | Sat Sep 7 | at Arizona St | L23-30 | 1-1 | .500 | Mountain America Stadium · Tempe, AZ |
| 3 | Sat Sep 14 | vs Toledo | L17-41 | 1-2 | .333 | Davis Wade Stadium · Starkville, MS |
| 4 | Sat Sep 21 | vs Florida | L28-45 | 1-3 | .250 | Davis Wade Stadium · Starkville, MS |
| 5 | Sat Sep 28 | at #1Texas | L13-35 | 1-4 | .200 | DKR-Texas Memorial Stadium · Austin, TX |
| 7 | Sat Oct 12 | at #5Georgia | L31-41 | 1-5 | .167 | Sanford Stadium · Athens, GA |
| 8 | Sat Oct 19 | vs #14Texas A&M | L24-34 | 1-6 | .143 | Davis Wade Stadium · Starkville, MS |
| 9 | Sat Oct 26 | vs Arkansas | L25-58 | 1-7 | .125 | Davis Wade Stadium · Starkville, MS |
| 10 | Sat Nov 2 | vs UMass | W45-20 | 2-7 | .222 | Davis Wade Stadium · Starkville, MS |
| 11 | Sat Nov 9 | at #7Tennessee | L14-33 | 2-8 | .200 | Neyland Stadium · Knoxville, TN |
| 13 | Sat Nov 23 | vs #23Missouri | L20-39 | 2-9 | .182 | Davis Wade Stadium · Starkville, MS |
| 14 | Fri Nov 29 | at #14Ole Miss | L14-26 | 2-10 | .167 | Vaught-Hemingway Stadium · Oxford, MS |
