| 1 | Sat Sep 3 | vs Troy | W28-10 | 1-0 | 1.000 | Vaught-Hemingway Stadium · Oxford, MS |
| 2 | Sat Sep 10 | vsC Arkansas | W59-3 | 2-0 | 1.000 | Vaught-Hemingway Stadium · Oxford, MS |
| 3 | Sat Sep 17 | atGeorgia Tech | W42-0 | 3-0 | 1.000 | Bobby Dodd Stadium · Atlanta, GA |
| 4 | Sat Sep 24 | vsTulsa | W35-27 | 4-0 | 1.000 | Vaught-Hemingway Stadium · Oxford, MS |
| 5 | Sat Oct 1 | vs#7Kentucky | W22-19 | 5-0 | 1.000 | Vaught-Hemingway Stadium · Oxford, MS |
| 6 | Sat Oct 8 | atVanderbilt | W52-28 | 6-0 | 1.000 | FirstBank Stadium · Nashville, TN |
| 7 | Sat Oct 15 | vsAuburn | W48-34 | 7-0 | 1.000 | Vaught-Hemingway Stadium · Oxford, MS |
| 8 | Sat Oct 22 | atLSU | L20-45 | 7-1 | .875 | Tiger Stadium · Baton Rouge, LA |
| 9 | Sat Oct 29 | atTexas A&M | W31-28 | 8-1 | .889 | Kyle Field · College Station, TX |
| 10 | Sat Nov 12 | vs#9Alabama | L24-30 | 8-2 | .800 | Vaught-Hemingway Stadium · Oxford, MS |
| 11 | Sat Nov 19 | atArkansas | L27-42 | 8-3 | .727 | Razorback Stadium · Fayetteville, AR |
| 12 | Thu Nov 24 | vsMississippi St | L22-24 | 8-4 | .667 | Vaught-Hemingway Stadium · Oxford, MS |
| BOWLS | Wed Dec 28 | vsTexas Tech | L25-42 | 8-5 | .615 | Vaught-Hemingway Stadium · Oxford, MS |
