| 1 | Tue Nov 7 | vs TBD | W111-46 | 1-0 | 1.000 | - | | American Bank Center · Corpus Christi, TX |
| 2 | Sat Nov 11 | at #7Houston | L50-82 | 1-1 | .500 | - | | Fertitta Center · Houston, TX |
| 3 | Mon Nov 13 | vsTBD | W104-45 | 2-1 | .667 | - | | American Bank Center · Corpus Christi, TX |
| 4 | Thu Nov 16 | at Texas Tech | L64-73 | 2-2 | .500 | - | | United Supermarkets Arena · Lubbock, TX |
| 5 | Wed Nov 22 | at N Kentucky | L73-88 | 2-3 | .400 | - | | Truist Arena · Highland Heights, KY |
| 6 | Fri Nov 24 | vs Long Island | L68-83 | 2-4 | .333 | - | | American Bank Center · Corpus Christi, TX |
| 7 | Wed Nov 29 | at UTEP | W67-63 | 3-4 | .429 | - | | Don Haskins Center · El Paso, TX |
| 8 | Wed Dec 6 | vs UT Rio Grande | L74-76 | 3-5 | .375 | - | | American Bank Center · Corpus Christi, TX |
| 9 | Sat Dec 9 | vs Omaha | W62-58 | 4-5 | .444 | - | | American Bank Center · Corpus Christi, TX |
| 10 | Fri Dec 15 | atUT Rio Grande | W86-76 | 5-5 | .500 | - | | UTRGV Fieldhouse · Edinburg, TX |
| 11 | Mon Dec 18 | vsTBD | W102-50 | 6-5 | .545 | - | | American Bank Center · Corpus Christi, TX |
| 12 | Fri Dec 22 | at #19Texas | L55-71 | 6-6 | .500 | - | LHN | Moody Center · Austin, TX |
| 13 | Sat Dec 30 | vsTBD | W84-61 | 7-6 | .538 | - | | American Bank Center · Corpus Christi, TX |
| 14 | Sat Jan 6 | at Incarnate Word | W75-65 | 8-6 | .571 | - | | Alice P. McDermott Convocation Center · San Antonio, TX |
| 15 | Mon Jan 8 | vs Hou Christian | W81-59 | 9-6 | .600 | - | | American Bank Center · Corpus Christi, TX |
| 16 | Sat Jan 13 | at New Orleans | L80-83 | 9-7 | .563 | - | | Lakefront Arena · New Orleans, LA |
| 17 | Mon Jan 15 | at SE Louisiana | W73-68 | 10-7 | .588 | - | | University Center (LA) · Hammond, LA |
| 18 | Sat Jan 20 | vs Nicholls | W69-59 | 11-7 | .611 | - | | American Bank Center · Corpus Christi, TX |
| 19 | Mon Jan 22 | vs McNeese | L61-62 | 11-8 | .579 | - | ESPNU | American Bank Center · Corpus Christi, TX |
| 20 | Sat Jan 27 | at N'Western St | W79-68 | 12-8 | .600 | - | | Prather Coliseum · Natchitoches, LA |
| 21 | Mon Jan 29 | at E Texas A&M | W69-54 | 13-8 | .619 | - | | The Field House · Commerce, TX |
| 22 | Sat Feb 3 | vs Lamar | W79-71 | 14-8 | .636 | - | | American Bank Center · Corpus Christi, TX |
| 23 | Sat Feb 10 | atMcNeese | L67-74 | 14-9 | .609 | - | | Legacy Center · Lake Charles, LA |
| 24 | Mon Feb 12 | atNicholls | L63-67 | 14-10 | .583 | - | | David R. Stopher Gymnasium · Thibodaux, LA |
| 25 | Sat Feb 17 | vsE Texas A&M | W86-63 | 15-10 | .600 | - | | American Bank Center · Corpus Christi, TX |
| 26 | Mon Feb 19 | vsN'Western St | W72-61 | 16-10 | .615 | - | | American Bank Center · Corpus Christi, TX |
| 27 | Sat Feb 24 | atLamar | W75-61 | 17-10 | .630 | - | | Montagne Center · Beaumont, TX |
| 28 | Mon Feb 26 | atHou Christian | W91-79 | 18-10 | .643 | - | | Sharp Gymnasium · Houston, TX |
| 29 | Sat Mar 2 | vsSE Louisiana | W80-68 | 19-10 | .655 | - | | American Bank Center · Corpus Christi, TX |
| 30 | Mon Mar 4 | vsNew Orleans | W73-60 | 20-10 | .667 | - | | American Bank Center · Corpus Christi, TX |
| 31 | Wed Mar 6 | vsIncarnate Word | W71-52 | 21-10 | .677 | - | | American Bank Center · Corpus Christi, TX |
| 32 | Tue Mar 12 | vsNicholls | L73-81 (OT) | 21-11 | .656 | - | | American Bank Center · Corpus Christi, TX |
| 33 | Tue Mar 19 | vs Abilene Chrstn | L63-73 | 21-12 | .636 | - | | American Bank Center · Corpus Christi, TX |
