| 1 | Sat Sep 3 | at Maryland | L10-31 | 0-1 | .000 | SECU Stadium · College Park, MD |
| 2 | Sat Sep 10 | vsHoly Cross | L31-37 | 0-2 | .000 | UB Stadium · Buffalo, NY |
| 3 | Sat Sep 17 | atCoast Car | L26-38 | 0-3 | .000 | Brooks Stadium (SC) · Conway, SC |
| 4 | Sat Sep 24 | atE Michigan | W50-31 | 1-3 | .250 | Rynearson Stadium · Ypsilanti, MI |
| 5 | Sat Oct 1 | vsMiami OH | W24-20 | 2-3 | .400 | UB Stadium · Buffalo, NY |
| 6 | Sat Oct 8 | atBowling Green | W38-7 | 3-3 | .500 | Doyt L. Perry Stadium · Bowling Green, OH |
| 7 | Sat Oct 15 | atUMass | W34-7 | 4-3 | .571 | Warren McGuirk Alumni Stadium · Amherst, MA |
| 8 | Sat Oct 22 | vsToledo | W34-27 | 5-3 | .625 | UB Stadium · Buffalo, NY |
| 9 | Tue Nov 1 | atOhio | L24-45 | 5-4 | .556 | Peden Stadium · Athens, OH |
| 10 | Wed Nov 9 | atC Michigan | L27-31 | 5-5 | .500 | Kelly/Shorts Stadium · Mount Pleasant, MI |
| 11 | Sat Nov 19 | vsAkron | PPD | 7-6 | .538 | UB Stadium · Buffalo, NY |
| 12 | Sat Nov 26 | vsKent State | L27-30 (OT) | 5-6 | .455 | UB Stadium · Buffalo, NY |
| 13 | Fri Dec 2 | vsAkron | W23-22 | 6-6 | .500 | UB Stadium · Buffalo, NY |
| BOWLS | Tue Dec 27 | vsGeorgia So | W23-21 | 7-6 | .538 | UB Stadium · Buffalo, NY |
