| 1 | Thu Aug 29 | vs Duquesne | W49-10 | 1-0 | 1.000 | Glass Bowl · Toledo, OH |
| 2 | Sat Sep 7 | vs UMass | W38-23 | 2-0 | 1.000 | Glass Bowl · Toledo, OH |
| 3 | Sat Sep 14 | at Mississippi St | W41-17 | 3-0 | 1.000 | Davis Wade Stadium · Starkville, MS |
| 4 | Sat Sep 21 | at Western KY | L21-26 | 3-1 | .750 | Houchens Industries-L.T. Smith Stadium · Bowling Green, KY |
| 6 | Sat Oct 5 | vs Miami OH | W30-20 | 4-1 | .800 | Glass Bowl · Toledo, OH |
| 7 | Sat Oct 12 | at Buffalo | L15-30 | 4-2 | .667 | UB Stadium · Buffalo, NY |
| 8 | Sat Oct 19 | at N Illinois | W13-6 | 5-2 | .714 | Huskie Stadium · Dekalb, IL |
| 9 | Sat Oct 26 | vs Bowling Green | L26-41 | 5-3 | .625 | Glass Bowl · Toledo, OH |
| 10 | Sat Nov 2 | at E Michigan | W29-28 | 6-3 | .667 | Rynearson Stadium · Ypsilanti, MI |
| 12 | Tue Nov 12 | vs C Michigan | W37-10 | 7-3 | .700 | Glass Bowl · Toledo, OH |
| 13 | Wed Nov 20 | vs Ohio | L7-24 | 7-4 | .636 | Glass Bowl · Toledo, OH |
| 14 | Tue Nov 26 | at Akron | L14-21 (OT) | 7-5 | .583 | InfoCision Stadium · Akron, OH |
| BOWLS | Thu Dec 26 | vs Pitt | W48-46 (6OT) | 8-5 | .615 | Glass Bowl · Toledo, OH |
