| 1 | Thu Aug 29 | vs Robert Morris | W38-10 | 1-0 | 1.000 | UB Stadium · Buffalo, NY |
| 2 | Sat Sep 7 | at#15Penn State | L13-45 | 1-1 | .500 | Beaver Stadium · University Park, PA |
| 3 | Sat Sep 14 | atLiberty | L17-35 | 1-2 | .333 | Williams Stadium (VA) · Lynchburg, VA |
| 4 | Sat Sep 21 | vsTemple | W38-22 | 2-2 | .500 | UB Stadium · Buffalo, NY |
| 5 | Sat Sep 28 | atMiami OH | L20-34 | 2-3 | .400 | Yager Stadium · Oxford, OH |
| 6 | Sat Oct 5 | vsOhio | L20-21 (OT) | 2-4 | .333 | UB Stadium · Buffalo, NY |
| 7 | Sat Oct 19 | atAkron | W21-0 | 3-4 | .429 | InfoCision Stadium · Akron, OH |
| 8 | Sat Oct 26 | vsC Michigan | W43-20 | 4-4 | .500 | UB Stadium · Buffalo, NY |
| 9 | Sat Nov 2 | atE Michigan | W43-14 | 5-4 | .556 | Rynearson Stadium · Ypsilanti, MI |
| 10 | Thu Nov 14 | atKent State | L27-30 | 5-5 | .500 | Dix Stadium · Kent, OH |
| 11 | Wed Nov 20 | vsToledo | W49-30 | 6-5 | .545 | UB Stadium · Buffalo, NY |
| 12 | Fri Nov 29 | vsBowling Green | W49-7 | 7-5 | .583 | UB Stadium · Buffalo, NY |
| BOWLS | Fri Dec 20 | atCharlotte | W31-9 | 8-5 | .615 | Jerry Richardson Stadium · Charlotte, NC |
