| 1 | Sat Aug 30 | vs Chattanooga | W45-10 | 1-0 | 1.000 | Simmons Bank Liberty Stadium · Memphis, TN |
| 2 | Sat Sep 6 | atGeorgia St | W38-16 | 2-0 | 1.000 | Center Parc Stadium · Atlanta, GA |
| 3 | Sat Sep 13 | atTroy | W28-7 | 3-0 | 1.000 | Veterans Memorial Stadium · Troy, AL |
| 4 | Sat Sep 20 | vsArkansas | W32-31 | 4-0 | 1.000 | Simmons Bank Liberty Stadium · Memphis, TN |
| 5 | Sat Sep 27 | atFAU | W55-26 | 5-0 | 1.000 | FAU Stadium · Boca Raton, FL |
| 6 | Sat Oct 4 | vsTulsa | W45-7 | 6-0 | 1.000 | Simmons Bank Liberty Stadium · Memphis, TN |
| 7 | Sat Oct 18 | atUAB | L24-31 | 6-1 | .857 | Legion Field (AL) · Birmingham, AL |
| 8 | Sat Oct 25 | vs#18South Florida | W34-31 | 7-1 | .875 | Simmons Bank Liberty Stadium · Memphis, TN |
| 9 | Fri Oct 31 | atRice | W38-14 | 8-1 | .889 | Rice Stadium · Houston, TX |
| 10 | Fri Nov 7 | vsTulane | L32-38 | 8-2 | .800 | Simmons Bank Liberty Stadium · Memphis, TN |
