| 1 | Sat Sep 5 | vs Arkansas St | W37-24 | 1-0 | 1.000 | Simmons Bank Liberty Stadium · Memphis, TN |
| 2 | Sat Oct 3 | atSMU | L27-30 | 1-1 | .500 | Gerald J. Ford Stadium · Dallas, TX |
| 3 | Sat Oct 17 | vsUCF | W50-49 | 2-1 | .667 | Simmons Bank Liberty Stadium · Memphis, TN |
| 4 | Sat Oct 24 | vsTemple | W41-29 | 3-1 | .750 | Simmons Bank Liberty Stadium · Memphis, TN |
| 5 | Sat Oct 31 | at#7Cincinnati | L10-49 | 3-2 | .600 | Nippert Stadium · Cincinnati, OH |
| 6 | Sat Nov 7 | vsSouth Florida | W34-33 | 4-2 | .667 | Simmons Bank Liberty Stadium · Memphis, TN |
| 7 | Sat Nov 14 | atNavy | PPD | 8-3 | .727 | Navy-Marine Corps Memorial Stadium · Annapolis, MD |
| 8 | Sat Nov 21 | vsSF Austin | W56-14 | 5-2 | .714 | Simmons Bank Liberty Stadium · Memphis, TN |
| 9 | Sat Nov 28 | atNavy | W10-7 | 6-2 | .750 | Navy-Marine Corps Memorial Stadium · Annapolis, MD |
| 10 | Sat Dec 5 | atTulane | L21-35 | 6-3 | .667 | Yulman Stadium · New Orleans, LA |
| 11 | Sat Dec 12 | vsHouston | W30-27 | 7-3 | .700 | Simmons Bank Liberty Stadium · Memphis, TN |
| BOWLS | Wed Dec 23 | atFAU | W25-10 | 8-3 | .727 | FAU Stadium · Boca Raton, FL |
