| 1 | Sat Sep 3 | vs UTEP | W45-13 | 1-0 | 1.000 | Memorial Stadium · Norman, OK |
| 2 | Sat Sep 10 | vs Kent State | W33-3 | 2-0 | 1.000 | Memorial Stadium · Norman, OK |
| 3 | Sat Sep 17 | at Nebraska | W49-14 | 3-0 | 1.000 | Memorial Stadium · Lincoln, NE |
| 4 | Sat Sep 24 | vs Kansas St | L34-41 | 3-1 | .750 | Memorial Stadium · Norman, OK |
| 5 | Sat Oct 1 | at TCU | L24-55 | 3-2 | .600 | Amon G. Carter Stadium · Fort Worth, TX |
| 6 | Sat Oct 8 | vs Texas | L0-49 | 3-3 | .500 | Memorial Stadium · Norman, OK |
| 7 | Sat Oct 15 | vs #19Kansas | W52-42 | 4-3 | .571 | Memorial Stadium · Norman, OK |
| 8 | Sat Oct 29 | at Iowa State | W27-13 | 5-3 | .625 | Jack Trice Stadium · Ames, IA |
| 9 | Sat Nov 5 | vs Baylor | L35-38 | 5-4 | .556 | Memorial Stadium · Norman, OK |
| 10 | Sat Nov 12 | at West Virginia | L20-23 | 5-5 | .500 | Milan Puskar Stadium · Morgantown, WV |
| 11 | Sat Nov 19 | vs #22Oklahoma St | W28-13 | 6-5 | .545 | Memorial Stadium · Norman, OK |
| 12 | Sat Nov 26 | at Texas Tech | L48-51 (OT) | 6-6 | .500 | Jones AT&T Stadium · Lubbock, TX |
| BOWLS | Thu Dec 29 | at #13Florida St | L32-35 | 6-7 | .462 | Doak Campbell Stadium · Tallahassee, FL |