| 1 | Sat Sep 2 | vs Arkansas St | W73-0 | 1-0 | 1.000 | Memorial Stadium · Norman, OK |
| 2 | Sat Sep 9 | vs SMU | W28-11 | 2-0 | 1.000 | Memorial Stadium · Norman, OK |
| 3 | Sat Sep 16 | at Tulsa | W66-17 | 3-0 | 1.000 | Chapman Stadium · Tulsa, OK |
| 4 | Sat Sep 23 | at Cincinnati | W20-6 | 4-0 | 1.000 | Nippert Stadium · Cincinnati, OH |
| 5 | Sat Sep 30 | vs Iowa State | W50-20 | 5-0 | 1.000 | Memorial Stadium · Norman, OK |
| 6 | Sat Oct 7 | at #3Texas | W34-30 | 6-0 | 1.000 | DKR-Texas Memorial Stadium · Austin, TX |
| 7 | Sat Oct 21 | vs UCF | W31-29 | 7-0 | 1.000 | Memorial Stadium · Norman, OK |
| 8 | Sat Oct 28 | at Kansas | L33-38 | 7-1 | .875 | David Booth Kansas Memorial Stadium · Lawrence, KS |
| 9 | Sat Nov 4 | at #22Oklahoma St | L24-27 | 7-2 | .778 | Boone Pickens Stadium · Stillwater, OK |
| 10 | Sat Nov 11 | vs West Virginia | W59-20 | 8-2 | .800 | Memorial Stadium · Norman, OK |
| 11 | Sat Nov 18 | at BYU | W31-24 | 9-2 | .818 | LaVell Edwards Stadium · Provo, UT |
| 12 | Fri Nov 24 | vs TCU | W69-45 | 10-2 | .833 | Memorial Stadium · Norman, OK |
| BOWLS | Thu Dec 28 | vs #14Arizona | L24-38 | 10-3 | .769 | Memorial Stadium · Norman, OK |