| 1 | Fri Aug 30 | at Army | L7-14 | 0-1 | .000 | Michie Stadium · West Point, NY |
| 2 | Fri Sep 6 | vsWake Forest | L21-41 | 0-2 | .000 | Rice Stadium · Houston, TX |
| 3 | Sat Sep 14 | vs#12Texas | L13-48 | 0-3 | .000 | Rice Stadium · Houston, TX |
| 4 | Sat Sep 21 | vsBaylor | L13-21 | 0-4 | .000 | Rice Stadium · Houston, TX |
| 5 | Sat Sep 28 | vsLouisiana Tech | L20-23 (OT) | 0-5 | .000 | Rice Stadium · Houston, TX |
| 6 | Sat Oct 5 | atUAB | L20-35 | 0-6 | .000 | Legion Field (AL) · Birmingham, AL |
| 7 | Sat Oct 19 | atUTSA | L27-31 | 0-7 | .000 | Alamodome · San Antonio, TX |
| 8 | Sat Oct 26 | vsSouthern Miss | L6-20 | 0-8 | .000 | Rice Stadium · Houston, TX |
| 9 | Sat Nov 2 | vsMarshall | L7-20 | 0-9 | .000 | Rice Stadium · Houston, TX |
| 10 | Sat Nov 16 | atMTSU | W31-28 | 1-9 | .100 | Johnny "Red" Floyd Stadium · Murfreesboro, TN |
| 11 | Sat Nov 23 | vsNorth Texas | W20-14 | 2-9 | .182 | Rice Stadium · Houston, TX |
| 12 | Sat Nov 30 | atUTEP | W30-16 | 3-9 | .250 | Sun Bowl · El Paso, TX |
