| 1 | Thu Aug 29 | vs NC A&T | W45-13 | 1-0 | 1.000 | Allegacy Federal Credit Union Stadium · Winston-Salem, NC |
| 2 | Sat Sep 7 | vs Virginia | L30-31 | 1-1 | .500 | Allegacy Federal Credit Union Stadium · Winston-Salem, NC |
| 3 | Sat Sep 14 | vs #5Ole Miss | L6-40 | 1-2 | .333 | Allegacy Federal Credit Union Stadium · Winston-Salem, NC |
| 5 | Sat Sep 28 | vs Louisiana | L38-41 | 1-3 | .250 | Allegacy Federal Credit Union Stadium · Winston-Salem, NC |
| 6 | Sat Oct 5 | at NC State | W34-30 | 2-3 | .400 | Carter-Finley Stadium · Raleigh, NC |
| 7 | Sat Oct 12 | vs #10Clemson | L14-49 | 2-4 | .333 | Allegacy Federal Credit Union Stadium · Winston-Salem, NC |
| 8 | Sat Oct 19 | at UConn | W23-20 | 3-4 | .429 | Pratt & Whitney Stadium · East Hartford, CT |
| 9 | Sat Oct 26 | at Stanford | W27-24 | 4-4 | .500 | Stanford Stadium · Stanford, CA |
| 11 | Fri Nov 8 | vs California | L36-46 | 4-5 | .444 | Allegacy Federal Credit Union Stadium · Winston-Salem, NC |
| 12 | Sat Nov 16 | at UNC | L24-31 | 4-6 | .400 | Kenan Stadium · Chapel Hill, NC |
| 13 | Sat Nov 23 | at #8Miami | L14-42 | 4-7 | .364 | Hard Rock Stadium · Miami Gardens, FL |
| 14 | Sat Nov 30 | vs Duke | L17-23 | 4-8 | .333 | Allegacy Federal Credit Union Stadium · Winston-Salem, NC |
