| 1 | Sat Aug 31 | vs Richmond | W34-13 | 1-0 | 1.000 | Scott Stadium · Charlottesville, VA |
| 2 | Sat Sep 7 | at Wake Forest | W31-30 | 2-0 | 1.000 | Allegacy Federal Credit Union Stadium · Winston-Salem, NC |
| 3 | Sat Sep 14 | vs Maryland | L13-27 | 2-1 | .667 | Scott Stadium · Charlottesville, VA |
| 4 | Sat Sep 21 | at Coast Car | W43-24 | 3-1 | .750 | Brooks Stadium (SC) · Conway, SC |
| 6 | Sat Oct 5 | vs Boston College | W24-14 | 4-1 | .800 | Scott Stadium · Charlottesville, VA |
| 7 | Sat Oct 12 | vs Louisville | L20-24 | 4-2 | .667 | Scott Stadium · Charlottesville, VA |
| 8 | Sat Oct 19 | at #10Clemson | L31-48 | 4-3 | .571 | Memorial Stadium · Clemson, SC |
| 9 | Sat Oct 26 | vs UNC | L14-41 | 4-4 | .500 | Scott Stadium · Charlottesville, VA |
| 11 | Sat Nov 9 | at #18Pitt | W24-19 | 5-4 | .556 | Acrisure Stadium · Pittsburgh, PA |
| 12 | Sat Nov 16 | at #8Notre Dame | L14-35 | 5-5 | .500 | Notre Dame Stadium · Notre Dame, IN |
| 13 | Sat Nov 23 | vs #13SMU | L7-33 | 5-6 | .455 | Scott Stadium · Charlottesville, VA |
| 14 | Sat Nov 30 | at Virginia Tech | L17-37 | 5-7 | .417 | Lane Stadium · Blacksburg, VA |
