| 1 | Sat Sep 2 | at #12Tennessee | L13-49 | 0-1 | .000 | Neyland Stadium · Knoxville, TN |
| 2 | Sat Sep 9 | vsJMU | L35-36 | 0-2 | .000 | Scott Stadium · Charlottesville, VA |
| 3 | Fri Sep 15 | atMaryland | L14-42 | 0-3 | .000 | SECU Stadium · College Park, MD |
| 4 | Fri Sep 22 | vsNC State | L21-24 | 0-4 | .000 | Scott Stadium · Charlottesville, VA |
| 5 | Sat Sep 30 | atBoston College | L24-27 | 0-5 | .000 | Alumni Stadium (Chestnut Hill, MA) · Chestnut Hill, MA |
| 6 | Sat Oct 7 | vsWilliam & Mary | W27-13 | 1-5 | .167 | Scott Stadium · Charlottesville, VA |
| 7 | Sat Oct 21 | at#10UNC | W31-27 | 2-5 | .286 | Kenan Stadium · Chapel Hill, NC |
| 8 | Sat Oct 28 | atMiami | L26-29 (OT) | 2-6 | .250 | Hard Rock Stadium · Miami Gardens, FL |
| 9 | Sat Nov 4 | vsGeorgia Tech | L17-45 | 2-7 | .222 | Scott Stadium · Charlottesville, VA |
| 10 | Thu Nov 9 | at#11Louisville | L24-31 | 2-8 | .200 | Cardinal Stadium · Louisville, KY |
| 11 | Sat Nov 18 | vsDuke | W30-27 | 3-8 | .273 | Scott Stadium · Charlottesville, VA |
| 12 | Sat Nov 25 | vsVirginia Tech | L17-55 | 3-9 | .250 | Scott Stadium · Charlottesville, VA |
