| 1 | Sat Aug 31 | at Vanderbilt | L27-34 (OT) | 0-1 | .000 | FirstBank Stadium · Nashville, TN |
| 2 | Sat Sep 7 | vs Marshall | W31-14 | 1-1 | .500 | Lane Stadium · Blacksburg, VA |
| 3 | Sat Sep 14 | at Old Dominion | W37-17 | 2-1 | .667 | S.B. Ballard Stadium · Norfolk, VA |
| 4 | Sat Sep 21 | vs Rutgers | L23-26 | 2-2 | .500 | Lane Stadium · Blacksburg, VA |
| 5 | Fri Sep 27 | at #7Miami | L34-38 | 2-3 | .400 | Hard Rock Stadium · Miami Gardens, FL |
| 6 | Sat Oct 5 | at Stanford | W31-7 | 3-3 | .500 | Stanford Stadium · Stanford, CA |
| 8 | Thu Oct 17 | vs Boston College | W42-21 | 4-3 | .571 | Lane Stadium · Blacksburg, VA |
| 9 | Sat Oct 26 | vs Georgia Tech | W21-6 | 5-3 | .625 | Lane Stadium · Blacksburg, VA |
| 10 | Sat Nov 2 | at Syracuse | L31-38 (OT) | 5-4 | .556 | JMA Wireless Dome · Syracuse, NY |
| 11 | Sat Nov 9 | vs #23Clemson | L14-24 | 5-5 | .500 | Lane Stadium · Blacksburg, VA |
| 13 | Sat Nov 23 | at Duke | L28-31 | 5-6 | .455 | Wallace Wade Stadium · Durham, NC |
| 14 | Sat Nov 30 | vs Virginia | W37-17 | 6-6 | .500 | Lane Stadium · Blacksburg, VA |
| BOWLS | Fri Jan 3 | vs Minnesota | L10-24 | 6-7 | .462 | Lane Stadium · Blacksburg, VA |
