| 1 | Sat Aug 30 | vs #9LSU | L10-17 | 0-1 | .000 | Memorial Stadium · Clemson, SC |
| 2 | Sat Sep 6 | vsTroy | W27-16 | 1-1 | .500 | Memorial Stadium · Clemson, SC |
| 3 | Sat Sep 13 | atGeorgia Tech | L21-24 | 1-2 | .333 | Bobby Dodd Stadium · Atlanta, GA |
| 4 | Sat Sep 20 | vsSyracuse | L21-34 | 1-3 | .250 | Memorial Stadium · Clemson, SC |
| 5 | Sat Oct 4 | atUNC | W38-10 | 2-3 | .400 | Kenan Stadium · Chapel Hill, NC |
| 6 | Sat Oct 11 | atBoston College | W41-10 | 3-3 | .500 | Alumni Stadium (Chestnut Hill, MA) · Chestnut Hill, MA |
| 7 | Sat Oct 18 | vsSMU | L24-35 | 3-4 | .429 | Memorial Stadium · Clemson, SC |
| 8 | Sat Nov 1 | vsDuke | L45-46 | 3-5 | .375 | Memorial Stadium · Clemson, SC |
| 9 | Sat Nov 8 | vsFlorida St | W24-10 | 4-5 | .444 | Memorial Stadium · Clemson, SC |
| 10 | Fri Nov 14 | at#20Louisville | W20-19 | 5-5 | .500 | Cardinal Stadium · Louisville, KY |
| 11 | Sat Nov 22 | vsFurman | W45-10 | 6-5 | .545 | Memorial Stadium · Clemson, SC |
| 12 | Sat Nov 29 | atSouth Carolina | W28-14 | 7-5 | .583 | Williams-Brice Stadium · Columbia, SC |
