| 2 | Sat Sep 12 | vs UCF | 3:30 PM | 1-0 | 1.000 | Acrisure Stadium · Pittsburgh, PA |
| 3 | Thu Sep 17 | vsSyracuse | 7:30 PM | 1-0 | 1.000 | Acrisure Stadium · Pittsburgh, PA |
| 4 | Sat Sep 26 | vsBucknell | 12:00 PM | 0-2 | .000 | Acrisure Stadium · Pittsburgh, PA |
| 5 | Fri Oct 2 | atVirginia Tech | 7:00 PM | 1-0 | 1.000 | Lane Stadium · Blacksburg, VA |
| 6 | Sat Oct 10 | vsUNC | TBD | 1-0 | 1.000 | Acrisure Stadium · Pittsburgh, PA |
| 7 | Sat Oct 17 | atBoston College | TBD | 1-1 | .500 | Alumni Stadium (Chestnut Hill, MA) · Chestnut Hill, MA |
| 8 | Sat Oct 24 | at7Miami | TBD | 2-0 | 1.000 | Hard Rock Stadium · Miami Gardens, FL |
| 9 | Sat Oct 31 | vsGeorgia Tech | TBD | 0-1 | .000 | Acrisure Stadium · Pittsburgh, PA |
| 10 | Fri Nov 13 | vsFlorida St | 7:00 PM | 1-1 | .500 | Acrisure Stadium · Pittsburgh, PA |
| 11 | Sat Nov 21 | at24Louisville | TBD | 1-1 | .500 | Cardinal Stadium · Louisville, KY |
| 12 | Sat Nov 28 | atCalifornia | TBD | 0-1 | .000 | California Memorial Stadium · Berkeley, CA |
