| Sat Nov 16 | vs #20Clemson | L20-24 | 7-3 | .700 | Acrisure Stadium · Pittsburgh, PA |
| Sat Nov 9 | vs Virginia | L19-24 | 7-2 | .778 | Acrisure Stadium · Pittsburgh, PA |
| Sat Nov 2 | at #20SMU | L25-48 | 7-1 | .875 | Gerald J. Ford Stadium · Dallas, TX |
| Thu Oct 24 | vs Syracuse | W41-13 | 7-0 | 1.000 | Acrisure Stadium · Pittsburgh, PA |
| Sat Oct 12 | vs California | W17-15 | 6-0 | 1.000 | Acrisure Stadium · Pittsburgh, PA |
| Sat Oct 5 | at UNC | W34-24 | 5-0 | 1.000 | Kenan Stadium · Chapel Hill, NC |
| Sat Sep 21 | vs Youngstown St | W73-17 | 4-0 | 1.000 | Acrisure Stadium · Pittsburgh, PA |
| Sat Sep 14 | vs West Virginia | W38-34 | 3-0 | 1.000 | Acrisure Stadium · Pittsburgh, PA |
| Sat Sep 7 | at Cincinnati | W28-27 | 2-0 | 1.000 | Nippert Stadium · Cincinnati, OH |
| Sat Aug 31 | vs Kent State | W55-24 | 1-0 | 1.000 | Acrisure Stadium · Pittsburgh, PA |
Louisville
Boston College