| 1 | Sat Sep 26 | vs Duke | W38-20 | 1-0 | 1.000 | Scott Stadium · Charlottesville, VA |
| 2 | Sat Oct 3 | at#1Clemson | L23-41 | 1-1 | .500 | Memorial Stadium · Clemson, SC |
| 3 | Sat Oct 10 | vsNC State | L21-38 | 1-2 | .333 | Scott Stadium · Charlottesville, VA |
| 4 | Sat Oct 17 | atWake Forest | L23-40 | 1-3 | .250 | Allegacy Federal Credit Union Stadium · Winston-Salem, NC |
| 5 | Sat Oct 24 | at#11Miami | L14-19 | 1-4 | .200 | Hard Rock Stadium · Miami Gardens, FL |
| 6 | Sat Oct 31 | vs#15UNC | W44-41 | 2-4 | .333 | Scott Stadium · Charlottesville, VA |
| 7 | Sat Nov 7 | vsLouisville | PPD | 5-5 | .500 | Scott Stadium · Charlottesville, VA |
| 8 | Sat Nov 14 | vsLouisville | W31-17 | 3-4 | .429 | Scott Stadium · Charlottesville, VA |
| 9 | Sat Nov 21 | vsAbilene Chrstn | W55-15 | 4-4 | .500 | Scott Stadium · Charlottesville, VA |
| 10 | Sat Nov 28 | atFlorida St | PPD | 5-5 | .500 | Doak Campbell Stadium · Tallahassee, FL |
| 11 | Sat Dec 5 | vsBoston College | W43-32 | 5-4 | .556 | Scott Stadium · Charlottesville, VA |
| 12 | Sat Dec 12 | atVirginia Tech | L15-33 | 5-5 | .500 | Lane Stadium · Blacksburg, VA |
