| 1 | Sat Aug 31 | at Pitt | W30-14 | 1-0 | 1.000 | Acrisure Stadium · Pittsburgh, PA |
| 2 | Fri Sep 6 | vsWilliam & Mary | W52-17 | 2-0 | 1.000 | Scott Stadium · Charlottesville, VA |
| 3 | Sat Sep 14 | vsFlorida St | W31-24 | 3-0 | 1.000 | Scott Stadium · Charlottesville, VA |
| 4 | Sat Sep 21 | vsOld Dominion | W28-17 | 4-0 | 1.000 | Scott Stadium · Charlottesville, VA |
| 5 | Sat Sep 28 | at#10Notre Dame | L20-35 | 4-1 | .800 | Notre Dame Stadium · Notre Dame, IN |
| 6 | Fri Oct 11 | atMiami | L9-17 | 4-2 | .667 | Hard Rock Stadium · Miami Gardens, FL |
| 7 | Sat Oct 19 | vsDuke | W48-14 | 5-2 | .714 | Scott Stadium · Charlottesville, VA |
| 8 | Sat Oct 26 | atLouisville | L21-28 | 5-3 | .625 | Cardinal Stadium · Louisville, KY |
| 9 | Sat Nov 2 | atUNC | W38-31 | 6-3 | .667 | Kenan Stadium · Chapel Hill, NC |
| 10 | Sat Nov 9 | vsGeorgia Tech | W33-28 | 7-3 | .700 | Scott Stadium · Charlottesville, VA |
| 11 | Sat Nov 23 | vsLiberty | W55-27 | 8-3 | .727 | Scott Stadium · Charlottesville, VA |
| 12 | Fri Nov 29 | vs#24Virginia Tech | W39-30 | 9-3 | .750 | Scott Stadium · Charlottesville, VA |
| 13 | Sat Dec 7 | at#3Clemson | L17-62 | 9-4 | .692 | Memorial Stadium · Clemson, SC |
| BOWLS | Mon Dec 30 | vs#9Florida | L28-36 | 9-5 | .643 | Scott Stadium · Charlottesville, VA |
