| 1 | Sat Sep 3 | vs BYU | L21-50 | 0-1 | .000 | Raymond James Stadium · Tampa, FL |
| 2 | Sat Sep 10 | vsHoward | W42-20 | 1-1 | .500 | Raymond James Stadium · Tampa, FL |
| 3 | Sat Sep 17 | at#18Florida | L28-31 | 1-2 | .333 | Ben Hill Griffin Stadium · Gainesville, FL |
| 4 | Sat Sep 24 | atLouisville | L3-41 | 1-3 | .250 | Cardinal Stadium · Louisville, KY |
| 5 | Sat Oct 1 | vsE Carolina | L28-48 | 1-4 | .200 | Raymond James Stadium · Tampa, FL |
| 6 | Sat Oct 8 | at#24Cincinnati | L24-28 | 1-5 | .167 | Nippert Stadium · Cincinnati, OH |
| 7 | Sat Oct 15 | vsTulane | L31-45 | 1-6 | .143 | Raymond James Stadium · Tampa, FL |
| 8 | Sat Oct 29 | atHouston | L27-42 | 1-7 | .125 | Robertson Stadium · Houston, TX |
| 9 | Sat Nov 5 | atTemple | L28-54 | 1-8 | .111 | Lincoln Financial Field · Philadelphia, PA |
| 10 | Sat Nov 12 | vsSMU | L23-41 | 1-9 | .100 | Raymond James Stadium · Tampa, FL |
| 11 | Fri Nov 18 | atTulsa | L42-48 | 1-10 | .091 | Chapman Stadium · Tulsa, OK |
| 12 | Sat Nov 26 | vs#22UCF | L39-46 | 1-11 | .083 | Raymond James Stadium · Tampa, FL |
