| 1 | Mon Nov 4 | vs TBD | W98-69 | 1-0 | 1.000 | - | ESPN+ | McBrayer Arena · Richmond, KY |
| 2 | Fri Nov 8 | at ETSU | W82-78 | 2-0 | 1.000 | - | ESPN+ | Freedom Hall Civic Center · Johnson City, TN |
| 3 | Tue Nov 12 | at Clemson | L62-75 | 2-1 | .667 | - | ACC Network | Littlejohn Coliseum · Clemson, SC |
| 4 | Tue Nov 19 | at Chicago St | W86-66 | 3-1 | .750 | - | | Jones Convocation Center · Chicago, IL |
| 5 | Mon Nov 25 | at Ball State | L61-63 | 3-2 | .600 | - | | Worthen Arena · Muncie, IN |
| 6 | Tue Nov 26 | at S Illinois | W77-72 | 4-2 | .667 | - | | Banterra Center · Carbondale, IL |
| 7 | Wed Nov 27 | at Louisiana Tech | L69-78 | 4-3 | .571 | - | | Thomas Assembly Center · Ruston, LA |
| 8 | Sun Dec 1 | at Troy | L74-84 | 4-4 | .500 | - | ESPN+ | Trojan Arena · Troy, AL |
| 9 | Fri Dec 6 | vsTBD | W98-62 | 5-4 | .556 | - | ESPN+ | McBrayer Arena · Richmond, KY |
| 10 | Wed Dec 11 | at Pitt | L56-96 | 5-5 | .500 | - | ESPN+ | Petersen Events Center · Pittsburgh, PA |
| 11 | Sat Dec 14 | vs E Illinois | W81-66 | 6-5 | .545 | - | ESPN+ | McBrayer Arena · Richmond, KY |
| 12 | Sat Dec 21 | vs J'Ville St | L80-91 | 6-6 | .500 | - | ESPN+ | McBrayer Arena · Richmond, KY |
| 13 | Sat Dec 28 | at Louisville | L76-78 | 6-7 | .462 | - | The CW Network | KFC Yum! Center · Louisville, KY |
| 14 | Thu Jan 2 | at C Arkansas | W89-83 (2OT) | 7-7 | .500 | - | ESPN+ | Farris Center · Conway, AR |
| 15 | Sat Jan 4 | at North Alabama | L67-88 | 7-8 | .467 | - | ESPN+ | Flowers Hall · Florence, AL |
| 16 | Thu Jan 9 | vs North Florida | W79-74 | 8-8 | .500 | - | ESPN+ | McBrayer Arena · Richmond, KY |
| 17 | Sat Jan 11 | vs Jacksonville | L75-82 | 8-9 | .471 | - | ESPN+ | McBrayer Arena · Richmond, KY |
| 18 | Thu Jan 16 | at Austin Peay | L90-97 (OT) | 8-10 | .444 | - | ESPN+ | Winfield Dunn Center · Clarksville, TN |
| 19 | Sat Jan 18 | vs Bellarmine | W72-69 | 9-10 | .474 | - | ESPN+ | McBrayer Arena · Richmond, KY |
| 20 | Thu Jan 23 | vs Stetson | L66-67 | 9-11 | .450 | - | ESPN+ | McBrayer Arena · Richmond, KY |
| 21 | Sat Jan 25 | vs FGCU | W81-77 | 10-11 | .476 | - | ESPN+ | McBrayer Arena · Richmond, KY |
| 22 | Thu Jan 30 | at Lipscomb | W80-71 | 11-11 | .500 | - | ESPN+ | Allen Arena · Nashville, TN |
| 23 | Sat Feb 1 | vsAustin Peay | W88-82 | 12-11 | .522 | - | ESPN+ | McBrayer Arena · Richmond, KY |
| 24 | Thu Feb 6 | atFGCU | W92-74 | 13-11 | .542 | - | ESPN+ | Alico Arena · Fort Myers, FL |
| 25 | Sat Feb 8 | atStetson | W83-58 | 14-11 | .560 | - | ESPN+ | Edmunds Center · Deland, FL |
| 26 | Thu Feb 13 | vs W Georgia | W95-73 | 15-11 | .577 | - | ESPN+ | McBrayer Arena · Richmond, KY |
| 27 | Sat Feb 15 | vs Queens | W86-80 (OT) | 16-11 | .593 | - | ESPN+ | McBrayer Arena · Richmond, KY |
| 28 | Tue Feb 18 | vsLipscomb | W66-57 | 17-11 | .607 | - | ESPN+ | McBrayer Arena · Richmond, KY |
| 29 | Thu Feb 20 | atBellarmine | L74-80 | 17-12 | .586 | - | ESPN+ | Knights Hall · Louisville, KY |
