| 1 | Mon Nov 3 | at Winthrop | L74-81 | 0-1 | .000 | - | YouTube | Winthrop Coliseum · Rock Hill, SC |
| 2 | Wed Nov 5 | vsTBD | W87-76 | 1-1 | .500 | - | ESPN+ | Curry Arena · Charlotte, NC |
| 3 | Sat Nov 8 | atVillanova | L74-94 | 1-2 | .333 | - | ESPN+ | Finneran Pavilion · Villanova, PA |
| 4 | Tue Nov 11 | atDuquesne | L81-87 (OT) | 1-3 | .250 | - | ESPN+ | UPMC Cooper Fieldhouse · Pittsburgh, PA |
| 5 | Sat Nov 15 | vsSacred Heart | W81-64 | 2-3 | .400 | - | ESPN+ | Curry Arena · Charlotte, NC |
| 6 | Thu Nov 20 | vsUNC Greensboro | W101-94 | 3-3 | .500 | - | ESPN+ | Curry Arena · Charlotte, NC |
| 7 | Sun Nov 23 | atFurman | L79-90 | 3-4 | .429 | - | ESPN+ | Timmons Arena · Greenville, SC |
| 8 | Fri Nov 28 | atVirginia | L69-94 | 3-5 | .375 | - | ACC Extra | John Paul Jones Arena · Charlottesville, VA |
| 9 | Wed Dec 3 | vsGardner-Webb | W107-74 | 4-5 | .444 | - | ESPN+ | Curry Arena · Charlotte, NC |
| 10 | Fri Dec 12 | vsSC State | W102-78 | 5-5 | .500 | - | ESPN+ | Curry Arena · Charlotte, NC |
| 11 | Sun Dec 14 | atWake Forest | L73-111 | 5-6 | .455 | - | ACC Extra | Lawrence Joel Veterans Memorial Coliseum · Winston-Salem, NC |
| 12 | Tue Dec 16 | at14Arkansas | L80-108 | 5-7 | .417 | - | SEC Network | Bud Walton Arena · Fayetteville, AR |
| 13 | Mon Dec 29 | atAuburn | L65-106 | 5-8 | .385 | - | SEC Network | Neville Arena · Auburn, AL |
| 14 | Thu Jan 1 | vsE Kentucky | W91-89 | 6-8 | .429 | - | ESPN+ | Curry Arena · Charlotte, NC |
| 15 | Sat Jan 3 | vsBellarmine | W98-76 | 7-8 | .467 | - | ESPN+ | Curry Arena · Charlotte, NC |
| 16 | Thu Jan 8 | atJacksonville | W77-51 | 8-8 | .500 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 17 | Sat Jan 10 | atNorth Florida | W89-82 | 9-8 | .529 | - | ESPN+ | UNF Arena · Jacksonville, FL |
| 18 | Thu Jan 15 | atFGCU | W85-74 | 10-8 | .556 | - | ESPN+ | Alico Arena · Fort Myers, FL |
| 19 | Sat Jan 17 | atStetson | W87-81 | 11-8 | .579 | - | ESPN+ | Edmunds Center · Deland, FL |
| 20 | Wed Jan 21 | vsNorth Alabama | W87-62 | 12-8 | .600 | - | ESPN+ | Curry Arena · Charlotte, NC |
| 21 | Sat Jan 24 | atW Georgia | L66-74 | 12-9 | .571 | - | ESPN+ | The Coliseum · Carrollton, GA |
| 22 | Wed Jan 28 | vsC Arkansas | L90-100 | 12-10 | .545 | - | ESPN+ | Curry Arena · Charlotte, NC |
| 23 | Sat Jan 31 | atBellarmine | L75-78 | 12-11 | .522 | - | ESPN+ | Knights Hall · Louisville, KY |
| 24 | Thu Feb 5 | vsJacksonville | W93-84 | 13-11 | .542 | - | ESPN+ | Curry Arena · Charlotte, NC |
| 25 | Sat Feb 7 | vsNorth Florida | W91-72 | 14-11 | .560 | - | ESPN+ | Curry Arena · Charlotte, NC |
| 26 | Wed Feb 11 | vsAustin Peay | L87-95 | 14-12 | .538 | - | ESPN+ | Curry Arena · Charlotte, NC |
| 27 | Sat Feb 14 | vsLipscomb | W87-81 | 15-12 | .556 | - | ESPN+ | Curry Arena · Charlotte, NC |
| 28 | Wed Feb 18 | atNorth Alabama | W85-78 | 16-12 | .571 | - | ESPN+ | Flowers Hall · Florence, AL |
| 29 | Sat Feb 21 | vsW Georgia | W91-84 | 17-12 | .586 | - | ESPN+ | Curry Arena · Charlotte, NC |
| 30 | Wed Feb 25 | atE Kentucky | W96-79 | 18-12 | .600 | - | ESPN+ | McBrayer Arena · Richmond, KY |
| 31 | Sat Feb 28 | atC Arkansas | L79-84 | 18-13 | .581 | - | ESPN+ | Farris Center · Conway, AR |
