| 1 | Mon Nov 4 | vs TBD | W78-65 | 1-0 | 1.000 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 2 | Thu Nov 7 | at #21Florida | L60-81 | 1-1 | .500 | - | ESPN+ | Exactech Arena at Stephen C. O'Connell Center · Gainesville, FL |
| 3 | Mon Nov 11 | at Furman | L69-78 | 1-2 | .333 | - | ESPN+ | Timmons Arena · Greenville, SC |
| 4 | Thu Nov 14 | vs SC State | W71-62 | 2-2 | .500 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 5 | Wed Nov 20 | at Virginia Tech | W74-64 | 3-2 | .600 | - | ESPN+ | Cassell Coliseum · Blacksburg, VA |
| 6 | Mon Nov 25 | vs Mercer | L89-90 (OT) | 3-3 | .500 | - | | Swisher Gymnasium · Jacksonville, FL |
| 7 | Tue Nov 26 | at Siena | W75-64 | 4-3 | .571 | - | | MVP Arena · Albany, NY |
| 8 | Sat Nov 30 | at Georgia | L56-102 | 4-4 | .500 | - | ESPN+ | Stegeman Coliseum · Athens, GA |
| 9 | Thu Dec 5 | vsTBD | W88-67 | 5-4 | .556 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 10 | Tue Dec 10 | at FAU | L63-85 | 5-5 | .500 | - | ESPN+ | FAU Arena · Boca Raton, FL |
| 11 | Sat Dec 14 | vs ETSU | W60-52 | 6-5 | .545 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 12 | Sat Dec 21 | at UCF | L66-86 | 6-6 | .500 | - | ESPN+ | Addition Financial Arena · Orlando, FL |
| 13 | Thu Jan 2 | vs Lipscomb | L65-70 | 6-7 | .462 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 14 | Sat Jan 4 | vs Austin Peay | W68-44 | 7-7 | .500 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 15 | Thu Jan 9 | at Bellarmine | W74-59 | 8-7 | .533 | - | ESPN+ | Knights Hall · Louisville, KY |
| 16 | Sat Jan 11 | at E Kentucky | W82-75 | 9-7 | .563 | - | ESPN+ | McBrayer Arena · Richmond, KY |
| 17 | Thu Jan 16 | vs North Alabama | W64-60 | 10-7 | .588 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 18 | Sat Jan 18 | vs C Arkansas | W72-62 | 11-7 | .611 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 19 | Thu Jan 23 | at W Georgia | W79-62 | 12-7 | .632 | - | ESPN+ | The Coliseum · Carrollton, GA |
| 20 | Sat Jan 25 | at Queens | W87-77 | 13-7 | .650 | - | ESPN+ | Curry Arena · Charlotte, NC |
| 21 | Wed Jan 29 | vs FGCU | L79-83 | 13-8 | .619 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 22 | Sat Feb 1 | vs North Florida | L78-81 | 13-9 | .591 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 23 | Thu Feb 6 | at Stetson | W74-65 | 14-9 | .609 | - | ESPN+ | Edmunds Center · Deland, FL |
| 24 | Sat Feb 8 | vsBellarmine | W73-64 | 15-9 | .625 | - | ESPN+ | Swisher Gymnasium · Jacksonville, FL |
| 25 | Thu Feb 13 | atC Arkansas | W77-62 | 16-9 | .640 | - | ESPN+ | Farris Center · Conway, AR |
| 26 | Sat Feb 15 | atNorth Alabama | L79-92 | 16-10 | .615 | - | ESPN+ | Flowers Hall · Florence, AL |
| 27 | Tue Feb 18 | atFGCU | L56-72 | 16-11 | .593 | - | ESPN+ | Alico Arena · Fort Myers, FL |
| 28 | Thu Feb 20 | atNorth Florida | L73-77 | 16-12 | .571 | - | ESPN+ | UNF Arena · Jacksonville, FL |
