| 1 | Mon Nov 4 | vs Chattanooga | W77-51 | 1-0 | 1.000 | - | BTN | Galen Center · Los Angeles, CA |
| 2 | Thu Nov 7 | vs Idaho St | W75-69 | 2-0 | 1.000 | - | B1G+ | Galen Center · Los Angeles, CA |
| 3 | Wed Nov 13 | vs UT Arlington | W98-95 | 3-0 | 1.000 | - | BTN | Galen Center · Los Angeles, CA |
| 4 | Sun Nov 17 | vs California | L66-71 | 3-1 | .750 | - | BTN | Galen Center · Los Angeles, CA |
| 5 | Wed Nov 20 | vs San Jose St | W82-68 | 4-1 | .800 | - | Peacock | Galen Center · Los Angeles, CA |
| 6 | Sun Nov 24 | vs Grambling | W80-69 | 5-1 | .833 | - | B1G+ | Galen Center · Los Angeles, CA |
| 7 | Thu Nov 28 | vs Saint Mary's | L36-71 | 5-2 | .714 | - | truTV | Galen Center · Los Angeles, CA |
| 8 | Fri Nov 29 | at New Mexico | L73-83 | 5-3 | .625 | - | | The Pit · Albuquerque, NM |
| 9 | Wed Dec 4 | vs #12Oregon | L60-68 | 5-4 | .556 | - | BTN | Galen Center · Los Angeles, CA |
| 10 | Sat Dec 7 | at Washington | W85-61 | 6-4 | .600 | - | BTN | Alaska Airlines Arena · Seattle, WA |
| 11 | Sun Dec 15 | vs Montana St | W89-63 | 7-4 | .636 | - | BTN | Galen Center · Los Angeles, CA |
| 12 | Wed Dec 18 | vs CSU Northridge | W90-69 | 8-4 | .667 | - | BTN | Galen Center · Los Angeles, CA |
| 13 | Sun Dec 22 | vs Southern | W82-51 | 9-4 | .692 | - | BTN | Galen Center · Los Angeles, CA |
| 14 | Sat Jan 4 | vs Michigan | L74-85 | 9-5 | .643 | - | FOX | Galen Center · Los Angeles, CA |
| 15 | Wed Jan 8 | at Indiana | L69-82 | 9-6 | .600 | - | BTN | Simon Skjodt Assembly Hall · Bloomington, IN |
| 16 | Sat Jan 11 | at #13Illinois | W82-72 | 10-6 | .625 | - | BTN | State Farm Center · Champaign, IL |
| 17 | Tue Jan 14 | vs Iowa | W99-89 | 11-6 | .647 | - | FS1 | Galen Center · Los Angeles, CA |
| 18 | Sat Jan 18 | vs #24Wisconsin | L69-84 | 11-7 | .611 | - | BTN | Galen Center · Los Angeles, CA |
| 19 | Wed Jan 22 | at Nebraska | W78-73 | 12-7 | .632 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 20 | Mon Jan 27 | vs UCLA | L76-82 | 12-8 | .600 | - | FS1 | Galen Center · Los Angeles, CA |
| 21 | Sat Feb 1 | vs #7Michigan St | W70-64 | 13-8 | .619 | - | Peacock | Galen Center · Los Angeles, CA |
| 22 | Tue Feb 4 | at Northwestern | L75-77 | 13-9 | .591 | - | BTN | Welsh-Ryan Arena · Evanston, IL |
| 23 | Fri Feb 7 | at #7Purdue | L72-90 | 13-10 | .565 | - | FS1 | Mackey Arena · West Lafayette, IN |
| 24 | Tue Feb 11 | vs Penn State | W92-67 | 14-10 | .583 | - | BTN | Galen Center · Los Angeles, CA |
| 25 | Sat Feb 15 | vs Minnesota | L66-69 | 14-11 | .560 | - | BTN | Galen Center · Los Angeles, CA |
| 26 | Thu Feb 20 | at #20Maryland | L71-88 | 14-12 | .538 | - | FS1 | XFINITY Center · College Park, MD |
| 27 | Sun Feb 23 | at Rutgers | L85-95 | 14-13 | .519 | - | FS1 | Jersey Mike’s Arena · Piscataway, NJ |
| 28 | Wed Feb 26 | vs Ohio State | L82-87 | 14-14 | .500 | - | BTN | Galen Center · Los Angeles, CA |
| 29 | Sat Mar 1 | atOregon | L61-82 | 14-15 | .483 | - | BTN | Matthew Knight Arena · Eugene, OR |
| 30 | Wed Mar 5 | vsWashington | W92-61 | 15-15 | .500 | - | BTN | Galen Center · Los Angeles, CA |
| 31 | Sat Mar 8 | atUCLA | L63-90 | 15-16 | .484 | - | FOX | Pauley Pavilion · Los Angeles, CA |
| 32 | Wed Mar 12 | atRutgers | W97-89 (2OT) | 16-16 | .500 | - | Peacock | Jersey Mike’s Arena · Piscataway, NJ |
| 33 | Thu Mar 13 | at#20Purdue | L71-76 | 16-17 | .485 | - | BTN | Mackey Arena · West Lafayette, IN |
| 34 | Tue Apr 1 | vs Tulane | W89-60 | 17-17 | .500 | - | FS1 | Galen Center · Los Angeles, CA |
| 35 | Thu Apr 3 | vs Villanova | L59-60 | 17-18 | .486 | - | FS1 | Galen Center · Los Angeles, CA |
