| 1 | Mon Nov 3 | vs E Washington | 10:30 PM | 10-22 | .313 | #12 | BTN | Pauley Pavilion · Los Angeles, CA |
| 2 | Fri Nov 7 | vsPepperdine | 10:30 PM | 13-22 | .371 | #12 | BTN | Pauley Pavilion · Los Angeles, CA |
| 3 | Mon Nov 10 | vsW Georgia | 10:00 PM | 6-25 | .194 | #12 | | Pauley Pavilion · Los Angeles, CA |
| 4 | Fri Nov 14 | vs#13Arizona | 10:00 PM | 24-13 | .649 | #12 | Peacock | Pauley Pavilion · Los Angeles, CA |
| 5 | Tue Nov 18 | vsSacramento St | 10:30 PM | 7-25 | .219 | #12 | | Pauley Pavilion · Los Angeles, CA |
| 6 | Fri Nov 21 | vsPresbyterian | 10:30 PM | 14-19 | .424 | #12 | | Pauley Pavilion · Los Angeles, CA |
| 7 | Tue Nov 25 | atCalifornia | 10:00 PM | 14-19 | .424 | #12 | ESPN | Chase Center · San Francisco, CA |
| 8 | Wed Dec 3 | atWashington | 11:00 PM | 13-18 | .419 | #12 | | Alaska Airlines Arena · Seattle, WA |
| 9 | Sat Dec 6 | vsOregon | 6:00 PM | 25-10 | .714 | #12 | | Pauley Pavilion · Los Angeles, CA |
| 10 | Sat Dec 13 | at#21Gonzaga | 11:30 PM | 26-9 | .743 | #12 | ESPN | McCarthey Athletic Center · Spokane, WA |
| 11 | Wed Dec 17 | vsArizona St | 10:30 PM | 13-20 | .394 | #12 | FS1 | Pauley Pavilion · Los Angeles, CA |
| 12 | Fri Dec 19 | vsCal Poly | 10:00 PM | 16-19 | .457 | #12 | | Pauley Pavilion · Los Angeles, CA |
| 13 | Tue Dec 23 | vsUC Riverside | 4:00 PM | 21-13 | .618 | #12 | | Pauley Pavilion · Los Angeles, CA |
| 14 | Sat Jan 3 | atIowa | 6:00 PM | 17-16 | .515 | #12 | | Carver-Hawkeye Arena · Iowa City, IA |
| 15 | Tue Jan 6 | at#24Wisconsin | 9:00 PM | 27-10 | .730 | #12 | | Kohl Center · Madison, WI |
| 16 | Sat Jan 10 | vsMaryland | 8:00 PM | 27-9 | .750 | #12 | | Pauley Pavilion · Los Angeles, CA |
| 17 | Wed Jan 14 | atPenn State | 8:30 PM | 16-15 | .516 | #12 | FS1 | Bryce Jordan Center · University Park, PA |
| 18 | Sat Jan 17 | atOhio State | 1:00 PM | 17-15 | .531 | #12 | | Value City Arena · Columbus, OH |
| 19 | Tue Jan 20 | vs#1Purdue | 10:00 PM | 24-12 | .667 | #12 | | Pauley Pavilion · Los Angeles, CA |
| 20 | Sat Jan 24 | vsNorthwestern | 6:00 PM | 17-16 | .515 | #12 | | Pauley Pavilion · Los Angeles, CA |
| 21 | Wed Jan 28 | atOregon | 11:00 PM | 25-10 | .714 | #12 | | Matthew Knight Arena · Eugene, OR |
| 22 | Sat Jan 31 | vsIndiana | 5:00 PM | 19-13 | .594 | #12 | | Pauley Pavilion · Los Angeles, CA |
| 23 | Tue Feb 3 | vsRutgers | 9:30 PM | 15-17 | .469 | #12 | | Pauley Pavilion · Los Angeles, CA |
| 24 | Sat Feb 7 | vsWashington | 10:00 PM | 13-18 | .419 | #12 | | Pauley Pavilion · Los Angeles, CA |
| 25 | Sat Feb 14 | at#7Michigan | 1:00 PM | 27-10 | .730 | #12 | | Crisler Center · Ann Arbor, MI |
| 26 | Tue Feb 17 | at#22Michigan St | 8:30 PM | 30-7 | .811 | #12 | | Breslin Center · East Lansing, MI |
| 27 | Sat Feb 21 | vs#17Illinois | 8:00 PM | 22-13 | .629 | #12 | | Pauley Pavilion · Los Angeles, CA |
| 28 | Tue Feb 24 | vsUSC | 11:00 PM | 17-18 | .486 | #12 | | Pauley Pavilion · Los Angeles, CA |
| 29 | Sat Feb 28 | atMinnesota | 2:00 PM | 15-17 | .469 | #12 | | Williams Arena · Minneapolis, MN |
| 30 | Tue Mar 3 | vsNebraska | 11:00 PM | 21-14 | .600 | #12 | FS1 | Pauley Pavilion · Los Angeles, CA |
| 31 | Sat Mar 7 | atUSC | 9:00 PM | 17-18 | .486 | #12 | | Galen Center · Los Angeles, CA |
