| 1 | Mon Nov 4 | vs Canisius | W93-64 | 1-0 | 1.000 | #10 | ESPN+ | McKale Center · Tucson, AZ |
| 2 | Sat Nov 9 | vs Old Dominion | W102-44 | 2-0 | 1.000 | #10 | ESPN+ | McKale Center · Tucson, AZ |
| 3 | Fri Nov 15 | at Wisconsin | L88-103 | 2-1 | .667 | #9 | Peacock | Kohl Center · Madison, WI |
| 4 | Fri Nov 22 | vs #12Duke | L55-69 | 2-2 | .500 | #17 | ESPN2 | McKale Center · Tucson, AZ |
| 5 | Wed Nov 27 | at Davidson | W104-71 | 3-2 | .600 | #24 | ESPNEWS | John M. Belk Arena · Davidson, NC |
| 6 | Thu Nov 28 | at Oklahoma | L77-82 | 3-3 | .500 | #24 | ESPN | Lloyd Noble Center · Norman, OK |
| 7 | Fri Nov 29 | at West Virginia | L76-83 (OT) | 3-4 | .429 | #24 | ESPN2 | WVU Coliseum · Morgantown, WV |
| 8 | Sat Dec 7 | vs Southern Utah | W102-66 | 4-4 | .500 | - | CBS | McKale Center · Tucson, AZ |
| 9 | Sat Dec 14 | vs #24UCLA | L54-57 | 4-5 | .444 | - | ESPN2 | McKale Center · Tucson, AZ |
| 10 | Wed Dec 18 | vs Samford | W96-64 | 5-5 | .500 | - | ESPN+ | McKale Center · Tucson, AZ |
| 11 | Sat Dec 21 | vs C Michigan | W94-41 | 6-5 | .545 | - | ESPN+ | McKale Center · Tucson, AZ |
| 12 | Mon Dec 30 | vs TCU | W90-81 | 7-5 | .583 | - | ESPN+ | McKale Center · Tucson, AZ |
| 13 | Sat Jan 4 | at #16Cincinnati | W72-67 | 8-5 | .615 | - | ESPN2 | Fifth Third Arena · Cincinnati, OH |
| 14 | Tue Jan 7 | at#21West Virginia | W75-56 | 9-5 | .643 | - | ESPN+ | WVU Coliseum · Morgantown, WV |
| 15 | Sat Jan 11 | vs UCF | W88-80 | 10-5 | .667 | - | ESPN | McKale Center · Tucson, AZ |
| 16 | Tue Jan 14 | vs #25Baylor | W81-70 | 11-5 | .688 | - | ESPN | McKale Center · Tucson, AZ |
| 17 | Sat Jan 18 | at Texas Tech | L54-70 | 11-6 | .647 | - | ESPN2 | United Supermarkets Arena · Lubbock, TX |
| 18 | Tue Jan 21 | at Oklahoma St | W92-78 | 12-6 | .667 | - | ESPNU | Gallagher-Iba Arena · Stillwater, OK |
| 19 | Sat Jan 25 | vs Colorado | W78-63 | 13-6 | .684 | - | ESPN+ | McKale Center · Tucson, AZ |
| 20 | Mon Jan 27 | vs #3Iowa State | W86-75 (OT) | 14-6 | .700 | - | ESPN | McKale Center · Tucson, AZ |
| 21 | Sat Feb 1 | at Arizona St | W81-72 | 15-6 | .714 | - | CBS | Desert Financial Arena · Tempe, AZ |
| 22 | Tue Feb 4 | at BYU | W85-74 | 16-6 | .727 | #20 | ESPN | Marriott Center · Provo, UT |
| 23 | Sat Feb 8 | vs#13Texas Tech | W82-73 | 17-6 | .739 | #20 | ESPNEWS | McKale Center · Tucson, AZ |
| 24 | Tue Feb 11 | at Kansas St | L70-73 | 17-7 | .708 | #13 | ESPN+ | Bramlage Coliseum · Manhattan, KS |
| 25 | Sat Feb 15 | vs #6Houston | L58-62 | 17-8 | .680 | #13 | ESPN | McKale Center · Tucson, AZ |
| 26 | Mon Feb 17 | atBaylor | W74-67 | 18-8 | .692 | #19 | ESPN | Ferrell Center · Waco, TX |
Utah
#23Kansas