| 1 | Mon Nov 3 | vs #3Florida | 7:00 PM | 36-4 | .900 | #13 | TNT | McKale Center · Tucson, AZ |
| 2 | Fri Nov 7 | vsUtah Tech | 9:00 PM | 7-26 | .212 | #13 | TNT | McKale Center · Tucson, AZ |
| 3 | Tue Nov 11 | vsN Arizona | 9:00 PM | 18-16 | .529 | #13 | ESPN+ | McKale Center · Tucson, AZ |
| 4 | Fri Nov 14 | at#12UCLA | 10:00 PM | 23-11 | .676 | #13 | Peacock | Pauley Pavilion · Los Angeles, CA |
| 5 | Wed Nov 19 | at#4UConn | 7:00 PM | 24-11 | .686 | #13 | FS1 | Gampel Pavilion · Storrs, CT |
| 6 | Mon Nov 24 | vsDenver | 10:30 PM | 11-21 | .344 | #13 | CBS | McKale Center · Tucson, AZ |
| 7 | Sat Nov 29 | vsNorfolk St | 4:00 PM | 24-11 | .686 | #13 | ESPN+ | McKale Center · Tucson, AZ |
| 8 | Sat Dec 6 | vs#20Auburn | 10:00 PM | 32-6 | .842 | #13 | ESPN | McKale Center · Tucson, AZ |
| 9 | Sat Dec 13 | at#15Alabama | 9:30 PM | 28-9 | .757 | #13 | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 10 | Tue Dec 16 | vsAbilene Chrstn | 9:00 PM | 16-16 | .500 | #13 | ESPN+ | McKale Center · Tucson, AZ |
| 11 | Sat Dec 20 | vsSDSU | 10:30 PM | 21-10 | .677 | #13 | ESPN2 | McKale Center · Tucson, AZ |
| 12 | Mon Dec 22 | vsBethune | 9:00 PM | 17-16 | .515 | #13 | ESPN+ | McKale Center · Tucson, AZ |
| 13 | Mon Dec 29 | vsS Dakota St | 9:00 PM | 20-12 | .625 | #13 | ESPN+ | McKale Center · Tucson, AZ |
| 14 | Sat Jan 3 | atUtah | 4:00 PM | 16-17 | .485 | #13 | Peacock | Jon M. Huntsman Center · Salt Lake City, UT |
| 15 | Wed Jan 7 | vsKansas St | 9:00 PM | 16-17 | .485 | #13 | FS1 | McKale Center · Tucson, AZ |
| 16 | Sat Jan 10 | atTCU | 4:00 PM | 16-16 | .500 | #13 | | Ed and Rae Schollmaier Arena · Fort Worth, TX |
| 17 | Wed Jan 14 | vsArizona St | 10:30 PM | 13-20 | .394 | #13 | FS1 | McKale Center · Tucson, AZ |
| 18 | Sat Jan 17 | atUCF | 4:00 PM | 20-17 | .541 | #13 | | Addition Financial Arena · Orlando, FL |
| 19 | Wed Jan 21 | vsCincinnati | 9:00 PM | 19-16 | .543 | #13 | FS1 | McKale Center · Tucson, AZ |
| 20 | Sat Jan 24 | vsWest Virginia | 2:00 PM | 19-13 | .594 | #13 | CBS | McKale Center · Tucson, AZ |
| 21 | Mon Jan 26 | at#8BYU | 9:00 PM | 26-10 | .722 | #13 | ESPN | Marriott Center · Provo, UT |
| 22 | Sat Jan 31 | atArizona St | 6:00 PM | 13-20 | .394 | #13 | ESPN2 | Desert Financial Arena · Tempe, AZ |
| 23 | Sat Feb 7 | vsOklahoma St | 4:00 PM | 17-18 | .486 | #13 | | McKale Center · Tucson, AZ |
| 24 | Mon Feb 9 | at#19Kansas | 9:00 PM | 21-13 | .618 | #13 | ESPN | Allen Fieldhouse · Lawrence, KS |
| 25 | Sat Feb 14 | vs#10Texas Tech | TBD | 28-9 | .757 | #13 | | McKale Center · Tucson, AZ |
| 26 | Wed Feb 18 | vs#8BYU | 9:00 PM | 26-10 | .722 | #13 | ESPN | McKale Center · Tucson, AZ |
| 27 | Sat Feb 21 | at#2Houston | 3:00 PM | 35-5 | .875 | #13 | ABC | Fertitta Center · Houston, TX |
| 28 | Tue Feb 24 | atBaylor | 9:00 PM | 20-15 | .571 | #13 | ESPN2 | Ferrell Center · Waco, TX |
| 29 | Sat Feb 28 | vs#19Kansas | TBD | 21-13 | .618 | #13 | ESPN | McKale Center · Tucson, AZ |
| 30 | Mon Mar 2 | vs#16Iowa State | 9:00 PM | 25-10 | .714 | #13 | ESPN | McKale Center · Tucson, AZ |
| 31 | Sat Mar 7 | atColorado | 11:00 PM | 14-21 | .400 | #13 | ESPN2 | CU Events Center · Boulder, CO |
