| 8 | Sat Dec 6 | vs #20Auburn | 10:00 PM | 7-2 | .778 | #2 | ESPN | McKale Center · Tucson, AZ |
| 9 | Sat Dec 13 | at#12Alabama | 9:30 PM | 6-2 | .750 | #2 | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 10 | Tue Dec 16 | vsAbilene Chrstn | 9:00 PM | 6-3 | .667 | #2 | ESPN+ | McKale Center · Tucson, AZ |
| 11 | Sat Dec 20 | vsSDSU | 10:30 PM | 4-3 | .571 | #2 | ESPN2 | McKale Center · Tucson, AZ |
| 12 | Mon Dec 22 | vsBethune | 9:00 PM | 2-6 | .250 | #2 | ESPN+ | McKale Center · Tucson, AZ |
| 13 | Mon Dec 29 | vsS Dakota St | 9:00 PM | 5-4 | .556 | #2 | ESPN+ | McKale Center · Tucson, AZ |
| 14 | Sat Jan 3 | atUtah | 4:00 PM | 6-3 | .667 | #2 | Peacock | Jon M. Huntsman Center · Salt Lake City, UT |
| 15 | Wed Jan 7 | vsKansas St | 9:00 PM | 5-3 | .625 | #2 | FS1 | McKale Center · Tucson, AZ |
| 16 | Sat Jan 10 | atTCU | 4:00 PM | 5-2 | .714 | #2 | | Ed and Rae Schollmaier Arena · Fort Worth, TX |
| 17 | Wed Jan 14 | vsArizona St | 10:30 PM | 6-2 | .750 | #2 | FS1 | McKale Center · Tucson, AZ |
| 18 | Sat Jan 17 | atUCF | 4:00 PM | 7-1 | .875 | #2 | | Addition Financial Arena · Orlando, FL |
| 19 | Wed Jan 21 | vsCincinnati | 9:00 PM | 6-2 | .750 | #2 | FS1 | McKale Center · Tucson, AZ |
| 20 | Sat Jan 24 | vsWest Virginia | 2:00 PM | 7-2 | .778 | #2 | CBS | McKale Center · Tucson, AZ |
| 21 | Mon Jan 26 | at#9BYU | 9:00 PM | 7-1 | .875 | #2 | ESPN | Marriott Center · Provo, UT |
| 22 | Sat Jan 31 | atArizona St | 2:00 PM | 6-2 | .750 | #2 | | Desert Financial Arena · Tempe, AZ |
| 23 | Sat Feb 7 | vsOklahoma St | 4:00 PM | 8-0 | 1.000 | #2 | | McKale Center · Tucson, AZ |
| 24 | Mon Feb 9 | at#21Kansas | 9:00 PM | 6-3 | .667 | #2 | ESPN | Allen Fieldhouse · Lawrence, KS |
| 25 | Sat Feb 14 | vs#19Texas Tech | TBD | 6-2 | .750 | #2 | | McKale Center · Tucson, AZ |
| 26 | Wed Feb 18 | vs#9BYU | 9:00 PM | 7-1 | .875 | #2 | ESPN | McKale Center · Tucson, AZ |
| 27 | Sat Feb 21 | at#8Houston | 3:00 PM | 7-1 | .875 | #2 | ABC | Fertitta Center · Houston, TX |
| 28 | Tue Feb 24 | atBaylor | 9:00 PM | 6-1 | .857 | #2 | ESPN2 | Ferrell Center · Waco, TX |
| 29 | Sat Feb 28 | vs#21Kansas | 4:00 PM | 6-3 | .667 | #2 | ESPN | McKale Center · Tucson, AZ |
| 30 | Mon Mar 2 | vs#10Iowa State | 9:00 PM | 8-0 | 1.000 | #2 | ESPN | McKale Center · Tucson, AZ |
| 31 | Sat Mar 7 | atColorado | 11:00 PM | 8-0 | 1.000 | #2 | ESPN2 | CU Events Center · Boulder, CO |
