| 9 | Sat Dec 6 | at Grand Canyon | 7:30 PM | 5-3 | .625 | - | CBSSN | GCU Arena · Phoenix, AZ |
| 10 | Sat Dec 13 | atOklahoma | 1:00 PM | 6-2 | .750 | - | FOX | Lloyd Noble Center · Norman, OK |
| 11 | Thu Dec 18 | vsKansas City | 8:00 PM | 1-7 | .125 | - | ESPN+ | Gallagher-Iba Arena · Stillwater, OK |
| 12 | Sun Dec 21 | vsFullerton | 2:00 PM | 3-5 | .375 | - | ESPN+ | Gallagher-Iba Arena · Stillwater, OK |
| 13 | Mon Dec 29 | vsBethune | 8:00 PM | 2-6 | .250 | - | ESPN+ | Gallagher-Iba Arena · Stillwater, OK |
| 14 | Sat Jan 3 | at#19Texas Tech | 1:00 PM | 6-2 | .750 | - | ESPN2 | United Supermarkets Arena · Lubbock, TX |
| 15 | Tue Jan 6 | vsUCF | 8:00 PM | 7-1 | .875 | - | ESPN+ | Gallagher-Iba Arena · Stillwater, OK |
| 16 | Sat Jan 10 | at#10Iowa State | 4:00 PM | 8-0 | 1.000 | - | | James H. Hilton Coliseum · Ames, IA |
| 17 | Tue Jan 13 | vsBaylor | 9:00 PM | 6-1 | .857 | - | CBSSN | Gallagher-Iba Arena · Stillwater, OK |
| 18 | Sat Jan 17 | vsKansas St | 10:00 PM | 5-3 | .625 | - | CBSSN | Gallagher-Iba Arena · Stillwater, OK |
| 19 | Tue Jan 20 | atTCU | 8:00 PM | 5-2 | .714 | - | ESPN+ | Ed and Rae Schollmaier Arena · Fort Worth, TX |
| 20 | Sat Jan 24 | vs#10Iowa State | 4:00 PM | 8-0 | 1.000 | - | Peacock | Gallagher-Iba Arena · Stillwater, OK |
| 21 | Sat Jan 31 | atUtah | 2:00 PM | 6-3 | .667 | - | ESPN2 | Jon M. Huntsman Center · Salt Lake City, UT |
| 22 | Wed Feb 4 | vs#9BYU | 9:00 PM | 7-1 | .875 | - | FS1 | Gallagher-Iba Arena · Stillwater, OK |
| 23 | Sat Feb 7 | at#2Arizona | 4:00 PM | 7-0 | 1.000 | - | | McKale Center · Tucson, AZ |
| 24 | Tue Feb 10 | atArizona St | 9:00 PM | 6-2 | .750 | - | CBSSN | Desert Financial Arena · Tempe, AZ |
| 25 | Sat Feb 14 | vsTCU | 12:00 PM | 5-2 | .714 | - | ESPN2 | Gallagher-Iba Arena · Stillwater, OK |
| 26 | Wed Feb 18 | vs#21Kansas | 9:00 PM | 6-3 | .667 | - | Peacock | Gallagher-Iba Arena · Stillwater, OK |
| 27 | Sat Feb 21 | atColorado | 3:30 PM | 8-0 | 1.000 | - | TNT | CU Events Center · Boulder, CO |
| 28 | Tue Feb 24 | vsWest Virginia | 7:00 PM | 7-2 | .778 | - | CBSSN | Gallagher-Iba Arena · Stillwater, OK |
| 29 | Sat Feb 28 | atCincinnati | 2:00 PM | 6-2 | .750 | - | CBSSN | Fifth Third Arena · Cincinnati, OH |
| 30 | Tue Mar 3 | atUCF | 7:00 PM | 7-1 | .875 | - | ESPN+ | Addition Financial Arena · Orlando, FL |
| 31 | Sat Mar 7 | vs#8Houston | 12:00 PM | 7-1 | .875 | - | CBS | Gallagher-Iba Arena · Stillwater, OK |
