| 1 | Tue Nov 5 | vs Idaho St | W55-48 | 1-0 | 1.000 | - | ESPN+ | Desert Financial Arena · Tempe, AZ |
| 2 | Fri Nov 8 | vs Santa Clara | W81-74 | 2-0 | 1.000 | - | FloSports | Desert Financial Arena · Tempe, AZ |
| 3 | Sun Nov 10 | at #6Gonzaga | L80-88 | 2-1 | .667 | - | ESPN | McCarthey Athletic Center · Spokane, WA |
| 4 | Thu Nov 14 | vs Grand Canyon | W87-76 | 3-1 | .750 | - | ESPN2 | Desert Financial Arena · Tempe, AZ |
| 5 | Sun Nov 17 | vs St Thomas (MN) | W81-66 | 4-1 | .800 | - | ESPN+ | Desert Financial Arena · Tempe, AZ |
| 6 | Wed Nov 20 | vs Cal Poly | W93-89 | 5-1 | .833 | - | ESPN+ | Desert Financial Arena · Tempe, AZ |
| 7 | Thu Nov 28 | at New Mexico | W85-82 | 6-1 | .857 | - | truTV | The Pit · Albuquerque, NM |
| 8 | Fri Nov 29 | vs Saint Mary's | W68-64 | 7-1 | .875 | - | | Desert Financial Arena · Tempe, AZ |
| 9 | Tue Dec 3 | vs San Diego | W90-53 | 8-1 | .889 | - | ESPN+ | Desert Financial Arena · Tempe, AZ |
| 10 | Sat Dec 14 | at #9Florida | L66-83 | 8-2 | .800 | - | SEC Network | Exactech Arena at Stephen C. O'Connell Center · Gainesville, FL |
| 11 | Sat Dec 21 | at UMass | W78-62 | 9-2 | .818 | - | CBS | William D. Mullins Memorial Center · Amherst, MA |
| 12 | Tue Dec 31 | at BYU | L56-76 | 9-3 | .750 | - | ESPN2 | Marriott Center · Provo, UT |
| 13 | Sat Jan 4 | vs Colorado | W81-61 | 10-3 | .769 | - | ESPN+ | Desert Financial Arena · Tempe, AZ |
| 14 | Wed Jan 8 | at #11Kansas | L55-74 | 10-4 | .714 | - | ESPN2 | Allen Fieldhouse · Lawrence, KS |
| 15 | Sat Jan 11 | vs Baylor | L66-72 (OT) | 10-5 | .667 | - | ESPN+ | Desert Financial Arena · Tempe, AZ |
| 16 | Tue Jan 14 | vs UCF | L89-95 | 10-6 | .625 | - | ESPNU | Desert Financial Arena · Tempe, AZ |
| 17 | Sat Jan 18 | at Cincinnati | L60-67 | 10-7 | .588 | - | CBS | Fifth Third Arena · Cincinnati, OH |
| 18 | Tue Jan 21 | at #23West Virginia | W65-57 | 11-7 | .611 | - | CBS | WVU Coliseum · Morgantown, WV |
| 19 | Sat Jan 25 | vs #3Iowa State | L61-76 | 11-8 | .579 | - | ESPN+ | Desert Financial Arena · Tempe, AZ |
| 20 | Tue Jan 28 | atColorado | W70-68 | 12-8 | .600 | - | ESPN+ | CU Events Center · Boulder, CO |
| 21 | Sat Feb 1 | vs Arizona | L72-81 | 12-9 | .571 | - | CBS | Desert Financial Arena · Tempe, AZ |
| 22 | Tue Feb 4 | vs Kansas St | L70-71 | 12-10 | .545 | - | ESPN+ | Desert Financial Arena · Tempe, AZ |
| 23 | Sun Feb 9 | at Oklahoma St | L73-86 | 12-11 | .522 | - | ESPN+ | Gallagher-Iba Arena · Stillwater, OK |
| 24 | Wed Feb 12 | at #12Texas Tech | L106-111 (2OT) | 12-12 | .500 | - | CBS | United Supermarkets Arena · Lubbock, TX |
| 25 | Sat Feb 15 | vs TCU | L70-74 | 12-13 | .480 | - | ESPN+ | Desert Financial Arena · Tempe, AZ |
| 26 | Tue Feb 18 | vs #5Houston | L65-80 | 12-14 | .462 | - | ESPN2 | Desert Financial Arena · Tempe, AZ |
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