| 1 | Mon Nov 7 | vs Tarleton | W62-59 | 1-0 | 1.000 | - | | Desert Financial Arena · Tempe, AZ |
| 2 | Thu Nov 10 | vsN Arizona | W84-68 | 2-0 | 1.000 | - | | Desert Financial Arena · Tempe, AZ |
| 3 | Sun Nov 13 | atTexas So | L66-67 (OT) | 2-1 | .667 | - | | H&PE Arena · Houston, TX |
| 4 | Wed Nov 16 | vsVCU | W63-59 | 3-1 | .750 | - | | Desert Financial Arena · Tempe, AZ |
| 5 | Thu Nov 17 | vsMichigan | W87-62 | 4-1 | .800 | - | ESPN2 | Desert Financial Arena · Tempe, AZ |
| 6 | Tue Nov 22 | vsGrambling | W80-49 | 5-1 | .833 | - | PACN | Desert Financial Arena · Tempe, AZ |
| 7 | Sun Nov 27 | vsAlcorn St | W76-54 | 6-1 | .857 | - | PACN | Desert Financial Arena · Tempe, AZ |
| 8 | Thu Dec 1 | atColorado | W60-59 | 7-1 | .875 | - | FS1 | CU Events Center · Boulder, CO |
| 9 | Sun Dec 4 | vsStanford | W68-64 | 8-1 | .889 | - | ESPN2 | Desert Financial Arena · Tempe, AZ |
| 10 | Wed Dec 7 | atSMU | W75-57 | 9-1 | .900 | - | ESPNU | Moody Coliseum · Dallas, TX |
| 11 | Mon Dec 12 | atCreighton | W73-71 | 10-1 | .909 | - | FS1 | CHI Health Center Omaha · Omaha, NE |
| 12 | Sun Dec 18 | vsSan Diego | W91-67 | 11-1 | .917 | - | | Desert Financial Arena · Tempe, AZ |
| 13 | Wed Dec 21 | atSan Francisco | L60-97 | 11-2 | .846 | #25 | CBS | War Memorial at the Sobrato Center · San Francisco, CA |
| 14 | Sat Dec 31 | vs#5Arizona | L60-69 | 11-3 | .786 | - | FOX | Desert Financial Arena · Tempe, AZ |
| 15 | Thu Jan 5 | vsWashington St | W77-71 | 12-3 | .800 | - | PACN | Desert Financial Arena · Tempe, AZ |
| 16 | Sun Jan 8 | vsWashington | W73-65 | 13-3 | .813 | - | ESPN | Desert Financial Arena · Tempe, AZ |
| 17 | Thu Jan 12 | atOregon | W90-73 | 14-3 | .824 | - | FS1 | Matthew Knight Arena · Eugene, OR |
| 18 | Sat Jan 14 | atOregon St | W74-69 | 15-3 | .833 | - | PACN | Gill Coliseum · Corvallis, OR |
| 19 | Thu Jan 19 | vs#5UCLA | L62-74 | 15-4 | .789 | - | FS1 | Desert Financial Arena · Tempe, AZ |
| 20 | Sat Jan 21 | vsUSC | L69-77 | 15-5 | .750 | - | ESPNU | Desert Financial Arena · Tempe, AZ |
| 21 | Thu Jan 26 | atWashington | L66-69 (OT) | 15-6 | .714 | - | ESPNU | Alaska Airlines Arena · Seattle, WA |
| 22 | Sat Jan 28 | atWashington St | L58-75 | 15-7 | .682 | - | ESPNU | Friel Court at Beasley Coliseum · Pullman, WA |
| 23 | Thu Feb 2 | vsOregon St | W68-57 | 16-7 | .696 | - | PACN | Desert Financial Arena · Tempe, AZ |
| 24 | Sat Feb 4 | vsOregon | L70-75 | 16-8 | .667 | - | ESPN2 | Desert Financial Arena · Tempe, AZ |
| 25 | Thu Feb 9 | atStanford | W69-65 | 17-8 | .680 | - | FS1 | Maples Pavilion · Stanford, CA |
| 26 | Sat Feb 11 | atCalifornia | W70-62 (OT) | 18-8 | .692 | - | PACN | Haas Pavilion · Berkeley, CA |
| 27 | Thu Feb 16 | vsColorado | L59-67 | 18-9 | .667 | - | PACN | Desert Financial Arena · Tempe, AZ |
| 28 | Sat Feb 18 | vsUtah | W67-59 | 19-9 | .679 | - | PACN | Desert Financial Arena · Tempe, AZ |
| 29 | Sat Feb 25 | at#7Arizona | W89-88 | 20-9 | .690 | - | CBS | McKale Center · Tucson, AZ |
| 30 | Thu Mar 2 | at#4UCLA | L61-79 | 20-10 | .667 | - | ESPN | Pauley Pavilion · Los Angeles, CA |
| 31 | Sat Mar 4 | atUSC | L65-68 | 20-11 | .645 | - | FS1 | Galen Center · Los Angeles, CA |
| 32 | Wed Mar 8 | vsOregon St | W63-57 | 21-11 | .656 | - | PACN | Desert Financial Arena · Tempe, AZ |
| 33 | Thu Mar 9 | atUSC | W77-72 | 22-11 | .667 | - | ESPN | Galen Center · Los Angeles, CA |
| 34 | Fri Mar 10 | atArizona | L59-78 | 22-12 | .647 | - | ESPN | McKale Center · Tucson, AZ |
| 35 | Wed Mar 15 | vs#11Nevada | W98-73 | 23-12 | .657 | #11 | truTV | Desert Financial Arena · Tempe, AZ |
| 36 | Fri Mar 17 | at#6TCU | L70-72 | 23-13 | .639 | #11 | truTV | Ed and Rae Schollmaier Arena · Fort Worth, TX |
