| 1 | Tue Nov 5 | vs Cal Poly | W86-78 | 1-0 | 1.000 | - | ESPN+ | War Memorial at the Sobrato Center · San Francisco, CA |
| 2 | Sat Nov 9 | vs Boise St | W84-73 | 2-0 | 1.000 | - | ESPN+ | War Memorial at the Sobrato Center · San Francisco, CA |
| 3 | Wed Nov 13 | vs Long Beach St | W84-54 | 3-0 | 1.000 | - | ESPN+ | War Memorial at the Sobrato Center · San Francisco, CA |
| 4 | Sat Nov 16 | vs Chicago St | W82-37 | 4-0 | 1.000 | - | ESPN+ | War Memorial at the Sobrato Center · San Francisco, CA |
| 5 | Thu Nov 21 | vs Memphis | L64-68 | 4-1 | .800 | - | ESPNU | War Memorial at the Sobrato Center · San Francisco, CA |
| 6 | Mon Nov 25 | vs Clemson | L55-70 | 4-2 | .667 | - | CBS | War Memorial at the Sobrato Center · San Francisco, CA |
| 7 | Tue Nov 26 | at Fordham | W85-64 | 5-2 | .714 | - | CBS | Rose Hill Gymnasium · Bronx, NY |
| 8 | Sun Dec 1 | vs Mercyhurst | W87-59 | 6-2 | .750 | - | ESPN+ | War Memorial at the Sobrato Center · San Francisco, CA |
| 9 | Thu Dec 5 | vs Saint Louis | W78-61 | 7-2 | .778 | - | ESPN+ | War Memorial at the Sobrato Center · San Francisco, CA |
| 10 | Wed Dec 11 | vs TBD | W68-52 | 8-2 | .800 | - | ESPN+ | War Memorial at the Sobrato Center · San Francisco, CA |
| 11 | Sun Dec 15 | at Loyola Chicago | W76-66 | 9-2 | .818 | - | ESPN+ | Joseph J. Gentile Arena · Chicago, IL |
| 12 | Wed Dec 18 | at Bradley | L64-66 | 9-3 | .750 | - | ESPN+ | Carver Arena · Peoria, IL |
| 13 | Sat Dec 21 | vs Montana | W71-67 | 10-3 | .769 | - | ESPN+ | War Memorial at the Sobrato Center · San Francisco, CA |
| 14 | Sat Dec 28 | vs LMU | W70-55 | 11-3 | .786 | - | ESPN+ | War Memorial at the Sobrato Center · San Francisco, CA |
| 15 | Mon Dec 30 | vs Santa Clara | W97-94 (OT) | 12-3 | .800 | - | ESPN+ | War Memorial at the Sobrato Center · San Francisco, CA |
| 16 | Thu Jan 2 | at Pacific | W89-81 | 13-3 | .813 | - | ESPN+ | Alex G. Spanos Center · Stockton, CA |
| 17 | Sat Jan 4 | at Washington St | L82-91 | 13-4 | .765 | - | ESPN+ | Friel Court at Beasley Coliseum · Pullman, WA |
| 18 | Thu Jan 9 | vs Portland | W81-72 | 14-4 | .778 | - | ESPN+ | War Memorial at the Sobrato Center · San Francisco, CA |
| 19 | Sat Jan 11 | atSanta Clara | L54-77 | 14-5 | .737 | - | ESPN+ | Leavey Center · Santa Clara, CA |
| 20 | Thu Jan 16 | at Pepperdine | W80-63 | 15-5 | .750 | - | ESPN+ | Firestone Fieldhouse · Malibu, CA |
| 21 | Sat Jan 18 | vs Oregon St | W81-70 | 16-5 | .762 | - | ESPN+ | War Memorial at the Sobrato Center · San Francisco, CA |
| 22 | Thu Jan 23 | at Saint Mary's | L51-71 | 16-6 | .727 | - | CBS | University Credit Union Pavilion · Moraga, CA |
| 23 | Sat Jan 25 | vs San Diego | W81-69 | 17-6 | .739 | - | ESPN+ | War Memorial at the Sobrato Center · San Francisco, CA |
| 24 | Sat Feb 1 | vsWashington St | W75-51 | 18-6 | .750 | - | ESPN+ | War Memorial at the Sobrato Center · San Francisco, CA |
| 25 | Thu Feb 6 | vsSaint Mary's | W65-64 | 19-6 | .760 | - | ESPN2 | War Memorial at the Sobrato Center · San Francisco, CA |
| 26 | Sat Feb 8 | atLMU | W72-66 | 20-6 | .769 | - | ESPN+ | Gersten Pavilion · Los Angeles, CA |
| 27 | Thu Feb 13 | at Gonzaga | L77-88 | 20-7 | .741 | - | ESPN | McCarthey Athletic Center · Spokane, WA |
| 28 | Sat Feb 15 | atSan Diego | W84-61 | 21-7 | .750 | - | ESPN+ | Jenny Craig Pavilion · San Diego, CA |
| 29 | Thu Feb 20 | vsPacific | W71-58 | 22-7 | .759 | - | ESPN+ | War Memorial at the Sobrato Center · San Francisco, CA |
