| Tue Nov 12 | at Iowa | 12:00 AM | 19-15 | .559 | Carver-Hawkeye Arena · Iowa City, IA |
| Wed Nov 27 | at Nebraska | 12:00 AM | 23-11 | .676 | Pinnacle Bank Arena · Lincoln, NE |
| Wed Dec 4 | vs Idaho St | 8:00 PM | 14-20 | .412 | Sanford Coyote Sports Center · Vermillion, SD |
| Sat Dec 7 | at N Arizona | 12:00 AM | 14-19 | .424 | J. Lawrence Walkup Skydome · Flagstaff, AZ |
| Thu Jan 2 | at Kansas City | 12:00 AM | 16-16 | .500 | Swinney Recreation Center · Kansas City, MO |
| Sat Jan 4 | vs Denver | 12:00 AM | 17-17 | .500 | Sanford Coyote Sports Center · Vermillion, SD |
| Sat Jan 11 | at St Thomas (MN) | 12:00 AM | 20-13 | .606 | Schoenecker Arena · Saint Paul, MN |
| Thu Jan 16 | vs Oral Roberts | 12:00 AM | 12-19 | .387 | Sanford Coyote Sports Center · Vermillion, SD |
| Sat Jan 18 | vs N Dakota St | 12:00 AM | 15-17 | .469 | Sanford Coyote Sports Center · Vermillion, SD |
| Thu Jan 23 | at North Dakota | 12:00 AM | 18-14 | .563 | Betty Engelstad Sioux Center · Grand Forks, ND |
| Sat Jan 25 | at S Dakota St | 12:00 AM | 22-13 | .629 | Frost Arena · Brookings, SD |
| Wed Jan 29 | vs Omaha | 12:00 AM | 15-18 | .455 | Sanford Coyote Sports Center · Vermillion, SD |
| Thu Feb 6 | atDenver | 12:00 AM | 17-17 | .500 | Hamilton Gymnasium · Denver, CO |
| Sat Feb 8 | atOral Roberts | 12:00 AM | 12-19 | .387 | Mabee Center · Tulsa, OK |
| Thu Feb 13 | vsKansas City | 12:00 AM | 16-16 | .500 | Sanford Coyote Sports Center · Vermillion, SD |
| Sat Feb 15 | vsS Dakota St | 12:00 AM | 22-13 | .629 | Sanford Coyote Sports Center · Vermillion, SD |
| Wed Feb 19 | vsSt Thomas (MN) | 12:00 AM | 20-13 | .606 | Sanford Coyote Sports Center · Vermillion, SD |
| Sat Feb 22 | atOmaha | 12:00 AM | 15-18 | .455 | Baxter Arena · Omaha, NE |
| Wed Feb 26 | atN Dakota St | 12:00 AM | 15-17 | .469 | Scheels Center · Fargo, ND |
| Sat Mar 1 | vsNorth Dakota | 12:00 AM | 18-14 | .563 | Sanford Coyote Sports Center · Vermillion, SD |
